Protein Alignment dlp and gpc6a

DIOPT Version :10

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_001103189.1
• Gene: gpc6a / 571904
• ZFINID: ZDB-GENE-071004-15
• Length: 562
• Species: Danio rerio
• Alignment Length: 677
• Identity: 219/677 - (32%)
• Similarity: 320/677 - (47%)
• Gaps: 156/677 - (23%)

  Fly    25 LVIFSSPLLLLLLTTHLPPTLQADNGPAPQVAALAAPNPAGGVAGSSIIDQFSPNCSAVTHIFQA 89
            :|:|:|..|||.|:.                        ||.|.        |.:||.|...|..
Zfish     6 VVVFTSLSLLLSLSC------------------------AGDVK--------SRSCSDVRLAFTT 38

  Fly    90 RGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKA 154
            :|.....:|.:..:...||.|....  ||||.:||.::..||:...|....|....:.....|:.
Zfish    39 KGFSLHNVPHQEISGEHLRVCAQGY--TCCTSDMEDQLGQQSKLDFERLVDDSSRNIRTTFTSRH 101

  Fly   155 TKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNT 219
            .||.:.|..||..|....|.||:||||.:|..||.:|.|||.||:.|:..|.|:|.||::.|::.
Zfish   102 KKFDEFFLELLDNSEKSLNDMFVRTYGKLYTHNSEMFEDLFSELKRYYTGGNVNLEEVLNDFWSR 166

  Fly   220 LYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVA 284
            |.::||.:||:|:||.::|:.|:|::..:||||||||.||..|:.::|:|.|::.|.|....|||
Zfish   167 LLERMFQLLNSQFTFSDDYLECISKYTDQLKPFGDVPRKLKAQVTKAFIAARSFVQGLMVGREVA 231

  Fly   285 KKVLNVRLNADCTGALTKMQHCGACKGYTE-KPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDK 348
            .:|..|.::..|:.|||||.:|..|.|.:. |||.|||.||::|||..|.:.|.||..|..||..
Zfish   232 NRVAKVNISPGCSKALTKMWYCPYCGGMSGLKPCANYCQNVMRGCLANQADLDPEWNLFIDAMLL 296

  Fly   349 VAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKRSISPKLQGV-Q 412
            ||:||.|.|||..|:||:::|||||||..||:...::::||||||.||...:.||    .:|: .
Zfish   297 VADRLEGPFNIEAVMEPIDVKISEAIMTMQDNSMQVSSKVFQGCGHPKAASVGRS----ARGISD 357

  Fly   413 ILNAR-----SPVEADTLDIDETLDE-AIVLRERRAAEPGSQETSAQQSQEQGVGKSGNGGGGGG 471
            :.|:|     ||.|..|.....:||. .||.|            :.|.|
Zfish   358 VFNSRFKPFNSPEERPTTAAGTSLDRLRIVWR------------TMQHS---------------- 394

  Fly   472 GNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWSNLPHS 536
                                                        |.||::::|:.::|||:||.|
Zfish   395 --------------------------------------------VVDIKEKLKESRRFWSSLPDS 415

  Fly   537 VCSNEDIASSSDVDGMCWNGHTIDRYMHSIT----TEHGSNPEFTGNPASTKQTAQMASQLSHLK 597
            :|:.:::....  :..|||.||..||...:.    |...:|||...:  .|:....:..|:..|:
Zfish   416 ICAEDEMTDPD--EEQCWNSHTRGRYFPEVVKDGLTNQLNNPEVEVD--ITRPDTFIRQQIMTLR 476

  Fly   598 NAIVHLRNAYNGQDVEW--SEQEELPYAGSGAGSGSGSEDDEDDDEGSGLGPFEPSHKPDV---E 657
            .....|||||||:||.:  |..||   :|||:|||..:|                   |:|   |
Zfish   477 VMTNKLRNAYNGKDVYFQDSSDEE---SGSGSGSGFTTE-------------------PEVVHTE 519

  Fly   658 RPSVDADNDDDE---DAGGRGHMPTHT 681
            .|.::||..|.:   |||.....|:.|
Zfish   520 PPMLEADKSDPQPPTDAGSVQQKPSVT 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..619	CDD:460084	187/553 (34%)
gpc6a	NP_001103189.1	Glypican	22..494	CDD:460084	189/561 (34%)