Protein Alignment dlp and gpc3

DIOPT Version :10

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_001292547.1
• Gene: gpc3 / 387365
• ZFINID: ZDB-GENE-031212-1
• Length: 590
• Species: Danio rerio
• Alignment Length: 657
• Identity: 140/657 - (21%)
• Similarity: 244/657 - (37%)
• Gaps: 156/657 - (23%)

  Fly    70 SSIIDQFSPNCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQ 134
            |.::|     |..|...||.........|:.|.:...|:.|: |...|||:..||.|..:.::|.
Zfish    25 SQVLD-----CREVRSSFQFLYPGMKWTPETPVSGSDLQVCQ-PKGLTCCSRKMEERYLLIAKQN 83

  Fly   135 LEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELE 199
            :|...:...:::.|::...|..|::.|..:|:..|.....:....:..:....|...:.||.::.
Zfish    84 MESSLQATSAQLKGLIIQNAALFQEAFDMVLRLGRNSTLMVLREEFPGLGAGASGAVTQLFLDMS 148

  Fly   200 TYFANGRVDLLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIK 264
            .|......::.:::..||:.|:...:..|............|:....|....:|..|..:..::.
Zfish   149 LYILGSDANVNDMVSTFFSRLFPLTYRRLLGNGAVAGISEECLRGAWKGSSAYGSFPKMMMTRLS 213

  Fly   265 RSFVATRTYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGYTE-KPCTNYCVNVIKGC 328
            ||.:|||.:.|||....||.....::|...||..:|.|:.:|..|:...| :||...||:.:..|
Zfish   214 RSLLATRVFLQALNLGIEVVNTTQHLRAGRDCGRSLLKLWYCPHCQSLLEARPCRPLCVSTMGAC 278

  Fly   329 LHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCG 393
            |....|....|..:...:..:|..:.|..:|..||..|::.|.:|:.....|
Zfish   279 LGGTTEVQPHWRAYVDELGSLAAAMKGEQDIEAVVLRLHVIIRQALKQAVAS------------- 330

  Fly   394 RPKLKKMKRSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQ 458
                   |..:|.::.|:.:   .:|.                 |..||....::.|||.
Zfish   331 -------KSKVSAQVSGMCV---HAPP-----------------RVSRAVPVSAEHTSAS----- 363

  Fly   459 GVGKSGNGGGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRV 523
                                          ...:||...:.|.:|:..||.       |:....:
Zfish   364 ------------------------------TVNHNRPPMNFDPDETLFGRR-------REFISGL 391

  Fly   524 KDYKKFWSNLPHSVCSNEDIASSSDVDGMCWNGHTI-DRY-------MHSITTEHGS-NPEFTGN 579
            :.:.:|:|.|..::||.|..:.:|   .:||||..: |::       :|    .||| :.:.|..
Zfish   392 RGFSQFYSGLGEALCSKEPTSLNS---SLCWNGQEMTDKFPGPGLKRVH----PHGSESKQKTPE 449

  Fly   580 PASTKQTAQMASQLSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGA---------------GS 629
            |.    .:|:..:|.|: |.::.:...   .:..|..::    .|.||               |.
Zfish   450 PV----ISQIIDKLKHI-NQLLRMVTL---PEKRWRARQ----GGGGARRNPSGPGQTDEDEEGL 502

  Fly   630 GSGSEDDEDDDEG-SGLGPFEPSHKPDVERPSVDADN---DD--------------DEDAG---- 672
            .||..||||:..| |||||  |..:..:...:..|||   ||              |...|
Zfish   503 ESGDCDDEDECTGVSGLGP--PPRRKRLRIFADLADNLAIDDLTLHELLLTPRLATDAHGGSSIP 565

  Fly   673 GRGHMPT 679
            |..|:||
Zfish   566 GAAHVPT 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..619	CDD:460084	110/549 (20%)
gpc3	NP_001292547.1	Glypican	12..515	CDD:460084	122/596 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	429..450		5/24 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..520		14/47 (30%)