Protein Alignment dlp and Gpc4

DIOPT Version :10

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_001014130.1
• Gene: Gpc4 / 317322
• RGDID: 1359399
• Length: 557
• Species: Rattus norvegicus
• Alignment Length: 650
• Identity: 211/650 - (32%)
• Similarity: 320/650 - (49%)
• Gaps: 131/650 - (20%)

  Fly    32 LLLLLLTTHLPPTLQADNGPAPQVAALAAPNPAGGVAGSSIIDQFSPNCSAVTHIFQARGIDAIE 96
            ||.||.|.            |...|:|.|..|.            |.:||.|..::.::|.:..:
  Rat     6 LLALLCTL------------AALSASLLAAEPK------------SKSCSEVRRLYVSKGFNKND 46

  Fly    97 IPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDIF 161
            .|....|...|:.|....  |||:..||.:.::||:...:....:|.:.:..|..|:..||.:.|
  Rat    47 APLYEINGDHLKICSQDY--TCCSQEMEEKYSLQSKDDFQTVVSEQCNHLQAIFASRYKKFDEFF 109

  Fly   162 TALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMFT 226
            ..||:.:....|.||::|||.:|.:||.:|.|||.||:.|:..|.|:|.|:::.|:..|.::||.
  Rat   110 KELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVAGNVNLEEMLNDFWARLLERMFR 174

  Fly   227 VLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLNVR 291
            ::|:||.|.:.|:.|||::.::||||||||.||.:|:.|:|||.||:.|.|..|.:|..:|..|.
  Rat   175 LVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVARDVVNRVSVVN 239

  Fly   292 LNADCTGALTKMQHCGACKG-YTEKPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVAERLLG 355
            ..|.||.||.||.:|..|:| .|.|||.|||.|:::|||..|.:.|.||.||..||..|||||.|
  Rat   240 PTAQCTQALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDLEWNNFIDAMLMVAERLEG 304

  Fly   356 SFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKRSISPKLQGVQILNARSPV 420
            .|||..|::|:::|||:||||.||:...::.:||||||.||                      |:
  Rat   305 PFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPK----------------------PL 347

  Fly   421 EADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGKSGNGGGGGGGNNRRQQQRRKQQQ 485
            .|..  |..::.|:......|...|..:.|:|       .|.|
  Rat   348 PAGR--ISRSISESAFSARFRPYHPEQRPTTA-------AGTS---------------------- 381

  Fly   486 QRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIASSSDVD 550
                                      |||:|.|:::::|..|||||:||.:||::|.:|:.::.:
  Rat   382 --------------------------LDRLVTDVKEKLKQAKKFWSSLPSTVCNDERMAAGNENE 420

  Fly   551 GMCWNGHTIDRYMHSIT----TEHGSNPEFTGNPASTKQTAQMASQLSHLKNAIVHLRNAYNGQD 611
            ..||||.:..||:.::|    ...|:|||...:  ::|....:..|:..|:.....::|||||.|
  Rat   421 DDCWNGKSKSRYLFAVTGNGLANQGNNPEVQVD--TSKPDILILRQIMALRVMTSKMKNAYNGND 483

  Fly   612 VEWSEQEELPYAGSGAGSGSGSEDDEDDDEGSGLGPFE---PSHKPDVERPSVDADNDDDEDAGG 673
            |::.:..:   ..||.|||||.|..:...|      ||   ..|       |..:.|:..:.|||
  Rat   484 VDFFDISD---ESSGEGSGSGCEYQQCPSE------FEYNATDH-------SGKSANEKADSAGG 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..619	CDD:460084	183/544 (34%)
Gpc4	NP_001014130.1	Glypican	24..550	CDD:460084	201/619 (32%)