Protein Alignment dlp and Gpc6

DIOPT Version :10

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_001073313.1
• Gene: Gpc6 / 23888
• MGIID: 1346322
• Length: 565
• Species: Mus musculus
• Alignment Length: 602
• Identity: 208/602 - (34%)
• Similarity: 304/602 - (50%)
• Gaps: 93/602 - (15%)

  Fly    79 NCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQI 143
            :||.|...:.|:|....:||.:......||.|  |...||||..||.:::.||:.:.|...::..
Mouse    29 SCSEVRQAYGAKGFSLADIPYQEIAGEHLRIC--PQEYTCCTTEMEDKLSQQSKLEFENLVEETS 91

  Fly   144 SRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVD 208
            ..:.....|:..||.:.|..||:.:....|.||:||||::|.:||.||.|||.||:.|:..|.|:
Mouse    92 HFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVN 156

  Fly   209 LLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTY 273
            |.|:::.|:..|.::||.::|.||.|.|:|:.|||::..:||||||||.||.:|:.|:|:|.||:
Mouse   157 LEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTF 221

  Fly   274 GQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGY-TEKPCTNYCVNVIKGCLHYQHEFDS 337
            .|.||...|||.:|..|.....|..||.||.:|..|:|. |.:||.|||:||:||||..|.:.|:
Mouse   222 VQGLTVGREVANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDT 286

  Fly   338 EWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKR 402
            ||..|..||..|||||.|.|||..|::|:::||||||||.|::...::.:||||||:||.....|
Mouse   287 EWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALR 351

  Fly   403 SISPKLQGVQILNARS-PVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGKSGNG 466
            |            ||| |...:|              ..|...|..:.|:|
Mouse   352 S------------ARSAPENFNT--------------RFRPYNPEERPTTA-------------- 376

  Fly   467 GGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWS 531
              .|...:|.:...|..|..                             |.||::::|..||.||
Mouse   377 --AGTSLDRLRTVWRTMQHS-----------------------------VTDIKEKLKLSKKVWS 410

  Fly   532 NLPHSVCSNEDIASSSDVDGMCWNGHTIDRYMHSI----TTEHGSNPEFTGNPASTKQTAQMASQ 592
            .||:::|.:|.:.:.:..:..|||||:..||:..|    .|...:|||...:  .|:....:..|
Mouse   411 ALPYTICKDERVTAGTSNEEECWNGHSKARYLPEIMNDGLTNQINNPEVEVD--ITRPDTFIRQQ 473

  Fly   593 LSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGAGSGSGSEDDEDDDEGSGLGPFEPSHKPDVE 657
            :..|:.....|:|||||.||.:.:..:   ..||:|||||..||....|      ||   ....|
Mouse   474 IMALRVMTNKLKNAYNGNDVNFQDTSD---ESSGSGSGSGCMDDVCPTE------FE---FVTTE 526

  Fly   658 RPSVDADNDDDEDAGGR 674
            .|:||.|..::|.:..:
Mouse   527 APAVDPDRREEESSASK 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..619	CDD:460084	190/545 (35%)
Gpc6	NP_001073313.1	Glypican	23..532	CDD:460084	205/589 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	348..376		10/53 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	490..511		9/23 (39%)