Protein Alignment dlp and gpc5b

DIOPT Version :10

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_001289150.1
• Gene: gpc5b / 101886726
• ZFINID: ZDB-GENE-060503-64
• Length: 610
• Species: Danio rerio
• Alignment Length: 645
• Identity: 151/645 - (23%)
• Similarity: 257/645 - (39%)
• Gaps: 125/645 - (19%)

  Fly    79 NCSAVTHIFQARGIDAIE-IPQKPSNERVLRYC--ESPSVGTCCTYNM-ETRMAMQSRQQLEGHT 139
            :|..|...||.|.:.::. :|:..:.:..|..|  :.|   ||||..| |:..:...|..|:...
Zfish    31 SCHEVKTAFQLRQVGSLRWVPETAATDAELLICKHQGP---TCCTRKMEESYYSAAQRDTLQNIL 92

  Fly   140 KDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYF-A 203
            .........||| .|:.|:|.|.:||..:....||:|..||..|.:....:.|.||.:|:.|. .
Zfish    93 SYSFELKYLILG-HASSFQDTFHSLLSFTLNHTNSLFDTTYETISQDARPLVSTLFNDLDLYLRG 156

  Fly   204 NGRVDLLEVMDKFFNTLYQKMFTVL------NTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQ 262
            :..|.:...:.:|::.|:..::..|      :...|:......|:.....::.|||..|.:|:..
Zfish   157 DDNVSVEHSVHRFYDKLFPLVYQHLVNPGLGSPVSTWSAEGTECLRATRHDIYPFGHHPQELAQG 221

  Fly   263 IKRSFVATRTYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGYT-EKPCTNYCVNVIK 326
            :.::.|..|...:||...::|.....:|.:...|..||.:|..|..|:|.| .:||...|:||::
Zfish   222 LSKALVVGRALSRALAVGADVLNITESVGMGRVCGRALVRMLFCPHCRGLTLIRPCGGLCLNVMR 286

  Fly   327 GCLHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQG 391
            |||....|.|:.|.::...::|::..|...:.:.:.:..:..:|::||:..|..|..::..|.:.
Zfish   287 GCLAGVAELDAPWRDYVSLLEKLSGALSERYEVELGLLRIRERINDAILTAQLHGPHLSAVVGKV 351

  Fly   392 CGRPKLKKMKRSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQ 456
            ||         |::   :.|....|.|.:.:.|..::.:|:               .:||...|.
Zfish   352 CG---------SLT---ESVSSTPANSTLGSLTPSVNPSLE---------------LQTSNTSSS 389

  Fly   457 EQGVGKSGNGGGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQ 521
            ...:..:||      .:.....:||....:..|....|.                |.:|.::...
Zfish   390 HTTLPDTGN------QHEHIALKRRSLPLKASKYDKPRS----------------LKKISKEFMG 432

  Fly   522 RVKDYKKFWSNLPHSVCSNEDIASSSDVDGMCWNGH-TIDRYMHSI------TTEHGSNPEF--- 576
            .::.||.|:||||..:|..|.:..    :..||:|. .::.|...:      ..:|  |||.
Zfish   433 YIQRYKSFFSNLPEMLCEGEVVMD----ENTCWSGEDVVESYTGHVVGNGLQAQKH--NPEIKVK 491

  Fly   577 TGNPASTKQTAQMASQLSHLKNAIVHLRN--------AYNGQDVEWSEQEELPYAGSGAGSGSGS 633
            |.||.           |..:|..:.|...        ...|.||:.|...|          |||.
Zfish   492 TANPV-----------LVSVKEMLEHFNQEMWATTGLGTGGTDVKESSSAE----------GSGE 535

  Fly   634 EDDEDDDEGSGLGPFEPSHK-----PDVERPS------VDADNDD---DEDAGGRGHMPT 679
            .||||..:|||.|. |..|.     ..|:.||      |...|:.   |....|..|:||
Zfish   536 CDDEDGCQGSGRGD-ERVHLTKENISSVQIPSQYGKIPVQPPNNGPKRDVQTSGVTHIPT 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..619	CDD:460084	127/569 (22%)
gpc5b	NP_001289150.1	Glypican	26..591	CDD:460084	148/640 (23%)