Protein Alignment dlp and gpc2

DIOPT Version :10

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: XP_031755392.1
• Gene: gpc2 / 100493961
• XenbaseID: XB-GENE-6258957
• Length: 567
• Species: Xenopus tropicalis
• Alignment Length: 664
• Identity: 184/664 - (27%)
• Similarity: 280/664 - (42%)
• Gaps: 157/664 - (23%)

  Fly    31 PLLLLLLTTHLPPTLQADNGPAPQVAALAAPNPAGGVAGSSIIDQFSPNCSAVTHIFQARGIDAI 95
            |||||                 |.:|. |||        ||:.|  :.:||......:.||:...
 Frog     8 PLLLL-----------------PLIAP-AAP--------SSLTD--TRSCSNTDRELRERGLGGT 44

  Fly    96 EIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDI 160
            ...:.|.:...||.|  |...||||...|.|::.:|.:.|.....:.:|...|.|.|...||...
 Frog    45 AGVRAPISGEHLRIC--PQEYTCCTSETEIRLSEESMRDLVRIVNESLSFPLGALTSGKKKFHKF 107

  Fly   161 FTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVD-LLEVMDKFFNTLYQKM 224
            |.|||..:....||||:.:||.:|.:|:.:||.||.||..|:..|... :.:.:.:|:..|.::.
 Frog   108 FLALLDAAEHSLNSMFVLSYGRLYSQNAALFSTLFSELRAYYMGGGASRVADALSEFWAGLLERT 172

  Fly   225 FTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLN 289
            ..:|..||....:||.|.:...:||:||||.|.:|.:||.|:..|.||..:.|.|.|::......
 Frog   173 LRLLLPQYQLGADYMECAARRAEELRPFGDSPRRLRLQITRALGAARTLVEGLGTGSDIVSGAAK 237

  Fly   290 VRLNADCTGALTKMQHCGACKGYTE-KPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVAERL 353
            .....||..|:.:|.:|..|:|:|. .||...|:||:||||.||.:.|.:|.:....:.:|||||
 Frog   238 AAPPPDCLRAVMRMWYCPLCRGHTNLHPCHGLCLNVLKGCLAYQADMDDDWNSLIDGLQEVAERL 302

  Fly   354 LGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKRSISPKLQGVQILNARS 418
            .|||||.:.:|.:.:|||||||:.|:....:|.::||.||.|...:.:||
 Frog   303 AGSFNIELAMESIAVKISEAIMSLQEESVQLTAQIFQTCGTPPPARSRRS--------------- 352

  Fly   419 PVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGKSGNGGGGGGGNNRRQQQRRKQ 483
                                      ||                                   :.
 Frog   353 --------------------------PG-----------------------------------ED 356

  Fly   484 QQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIASSSD 548
            .:||.:..||     |:...|..|..  :||:|.:|..:::..:..|..||.|:||:..:::...
 Frog   357 PRQRFRAYNN-----DEKPTSADGTN--IDRLVSEIVGKLRPLRGLWKLLPRSLCSDNRVSAGLS 414

  Fly   549 VDGMCWNGHTIDRYMHSITTE----HGSNP--EFTGNPASTKQTAQMASQLSHLKNAIVHLRNAY 607
            ....||||....||:..:..:    ..:||  |...:||..: |..:..|   |:.|.:.||.||
 Frog   415 NQEKCWNGQNRGRYLPQVAGDGLINQINNPEVELQMSPADPR-TRSLGPQ---LRLARMKLRAAY 475

  Fly   608 NGQDVEWSEQEELPYAGSGAGSGSGSEDDEDDDEGSGLGPFE-PSHKPDV----------ERPSV 661
            :|.|                   |.::|..|||...|.|..: .:.||..          :||.
 Frog   476 SGHD-------------------SDTQDVYDDDGSGGSGDGDIATDKPVTRTVAGGTQRKDRPG- 520

  Fly   662 DADNDDDEDAGGRG 675
             .:...:...||||
 Frog   521 -KNKKQNNSGGGRG 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..619	CDD:460084	156/547 (29%)
gpc2	XP_031755392.1	Glypican	26..484	CDD:460084	157/565 (28%)