DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stwl and hng2

DIOPT Version :9

Sequence 1:	NP_001261839.1	Gene:	stwl / 39581	FlyBaseID:	FBgn0003459	Length:	1037	Species:	Drosophila melanogaster
Sequence 2:	NP_649837.1	Gene:	hng2 / 41056	FlyBaseID:	FBgn0037634	Length:	254	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	63/270 - (23%)
Similarity:	108/270 - (40%)	Gaps:	76/270 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SAASEVNLML---LRSVEKQTALYDRTDENYRKRLPSENAWDMVASEV------------GESVE 51
            ||.|.:...:   :.:|.|::.:::|:..|:..|...:.||..:..|:            .|.|:
  Fly     9 SAGSNLRYSMYEFIDAVHKRSIIWERSHPNFHNRELRDEAWQQIGHELCSNFDDSSEPEKQEIVK 73

  Fly    52 KCKRRWRQLRNDYTRWCNADANR-RRNGQR--RLAYPLADELRFLDRHLNIADDMAADDDRSVSS 113
            ...:||:..|:.|.|     .|| |::|:.  |.:|....||.||   ||:..:  ::||
  Fly    74 TLLKRWKNTRDSYLR-----VNRLRQSGEEVARASYIYEKELSFL---LNVKAE--SEDD----- 123

  Fly   114 DKDRDNNRDSEGVDHHAQASLKERASSTSKLVKEVKLASQ---VRKEKSSQDKRENWENPGDKQR 175
                             ..||||:....:|. |.|..|:|   ....|.:.|:..|.| |..:..
  Fly   124 -----------------VESLKEQPKPQAKR-KRVSTAAQRSAKTPRKRNSDQESNIE-PAIRNP 169

  Fly   176 SRKKSAEEKLNDL----EESDEPE--KVPELDS---------FLQSDNEDDECMD--EEHLEDL- 222
            :...:....|.||    |::..||  .:|:|.|         :|.:| .|....|  :.|::.:
  Fly   170 AIPSNINTVLGDLGCAKEDTATPEIAYIPQLPSDPPCSTNTAYLSAD-PDQAFFDTIKPHMQQMC 233

  Fly   223 --EGFDFDLE 230
              ...||.:|
  Fly   234 ADRKLDFQIE 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stwl	NP_001261839.1	MADF	11..98	CDD:214738	25/104 (24%)
stwl	NP_001261839.1	BESS	604..637	CDD:281011
hng2	NP_649837.1	MADF_DNA_bdg	21..113	CDD:287510	23/96 (24%)
hng2	NP_649837.1	BESS	216..250	CDD:281011	7/29 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001895
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000