Protein Alignment D and Sox8

DIOPT Version :10

• Sequence 1: NP_524066.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001100459.1
• Gene: Sox8 / 302993
• RGDID: 1309072
• Length: 463
• Species: Rattus norvegicus
• Alignment Length: 344
• Identity: 103/344 - (29%)
• Similarity: 148/344 - (43%)
• Gaps: 66/344 - (19%)

  Fly    44 HYSQSLAAMGGSPNGPAGQGVNGSSGMGH--HMSSHMTPHHMHQAVSAQQTLSPNSSIGSAGSLG 106
            |...|.:....||.|..|.|..|..|.|.  ..:....|..:..|||  |.|.     |...||.
  Rat    24 HVEDSDSDAPPSPAGSEGLGRAGGGGRGDTAEAADERFPACIRDAVS--QVLK-----GYDWSLV 81

  Fly   107 SQSSLGSNGSGLNSSSGHQSAGMHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSE 171
            .....|..|..|.:                  :.|:||||||||||::..||::|...|.:||:|
  Rat    82 PMPVRGGGGGTLKA------------------KPHVKRPMNAFMVWAQAARRKLADQYPHLHNAE 128

  Fly   172 ISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAGPQGGLQMQAGGM 236
            :||.||..|:||:|||||||::||:|||..|.|:||||||:|||: |:..|    |.....:|
  Rat   129 LSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRR-KSVKT----GRSDSDSG-- 186

  Fly   237 GQQKLGAGPGAGAGGYNPFHQLPPYFAPSH-HLD-----QGYPVPYFGGFDPLALSKLHQSQAAA 295
              .:||..||      .|.::.......:| |.|     .|.|.|     .....:.|||:...:
  Rat   187 --TELGHHPG------GPMYKTDTVLGDAHRHSDHTGQTHGPPTP-----PTTPKTDLHQASNGS 238

  Fly   296 AAAVNNQGQQ---QGQAPPQLPPTSLSSFYSGIYSGISAPSLYA--------AHSANAAGLYPSS 349
            ...:..:|::   .|:.........:|...|.:.|.:....::.        .|||.|.  .||.
  Rat   239 KQELRLEGRRLVDSGRQNIDFSNVDISELSSEVISNMDTFDVHEFDQYLPLNGHSALAT--EPSQ 301

  Fly   350 STSSPGSSPGTITPNGMDG 368
            :|:|......:.:.:|..|
  Rat   302 ATASGSYGGASYSHSGATG 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_524066.1	HMG-box_SoxB	140..219	CDD:438790	48/78 (62%)
Sox8	NP_001100459.1	Sox_N	18..86	CDD:463586	19/68 (28%)
		HMG-box_SoxE	98..172	CDD:438840	46/73 (63%)