Protein Alignment Sox21a and sox18

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: XP_017209261.1
• Gene: sox18 / 797246
• ZFINID: ZDB-GENE-080725-1
• Length: 431
• Species: Danio rerio
• Alignment Length: 383
• Identity: 115/383 - (30%)
• Similarity: 165/383 - (43%)
• Gaps: 95/383 - (24%)

  Fly    60 GSGNTTPPP--------MPPADLAVPPAAPTPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHN 116
            |:.::||.|        ....:||..|.:.|....:..... ..|:.....|.:.:..::.....
Zfish    26 GASSSTPGPERGHGFDRSRTTELAPVPGSGTRTVSRTAAEA-RTGSPDSTRPGALTLGSSEGKSG 89

  Fly   117 SHDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALH 181
            ....|:|||||||||::.:|:::|..||.:||:.:||.||..||.|:...||||::||:|||..|
Zfish    90 GESRIRRPMNAFMVWAKDERKRLAIQNPDLHNAVLSKMLGQSWKALSTLDKRPFVEEAERLRLQH 154

  Fly   182 MKEHPDYKYRPRRK--PKTLNKSPVPG----GGGGGGGGGANGGVN--------AGGAGNSGPSG 232
            :::||:||||||||  ||.: |...||    |...||.|.|.....        .|...:..|||
Zfish   155 LQDHPNYKYRPRRKKQPKKM-KRVEPGLLLQGLAHGGPGDAYSPHRHAHHLLPPLGHFRDLHPSG 218

  Fly   233 P---GSVGSPKDMQPQLSPL-------GQSL---PHL------------HGHPHQSPYQSHPHHP 272
            .   .|.|.|   .|::|||       |.|:   ||:            |.||:..|    .|||
Zfish   219 APELESFGLP---TPEMSPLDVLEEGGGDSVFFPPHMQEDVGLSSWINYHQHPNHQP----GHHP 276

  Fly   273 HPHPHHVQLAAATLSAKYGFGSPLELSLP--------RLPNAFPGLAHYPLDPTLALDLQARLQA 329
            |.:.|::|.:...|:.|    ||| ..||        ..||  ||    .|.|.:.|...::  |
Zfish   277 HHNSHNLQHSHPHLNQK----SPL-ACLPLQEKCLVVESPN--PG----GLYPNMTLPESSK--A 328

  Fly   330 MYAGSIYHPWRYLPLISPETPPSPPSSSGTGISSYGCVKSEKSSPNAVVASAASPPNI 387
            .|.|.||          ..:.|.|..:|..|..|        ..|.....:..:||::
Zfish   329 GYYGQIY----------GSSQPQPAFTSHLGQLS--------PPPETSAVAQVAPPSL 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	44/80 (55%)
sox18	XP_017209261.1	HMG-box_SoxF_SOX18	91..170	CDD:438851	43/78 (55%)
		Sox17_18_mid	211..261	CDD:463454	14/52 (27%)
		PHA03420	<264..>315	CDD:177648	21/65 (32%)