Protein Alignment Sox21a and sox4

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001039084.1
• Gene: sox4 / 733893
• XenbaseID: XB-GENE-480727
• Length: 387
• Species: Xenopus tropicalis
• Alignment Length: 349
• Identity: 112/349 - (32%)
• Similarity: 153/349 - (43%)
• Gaps: 88/349 - (25%)

  Fly   101 NAPTSHSNSNTGSHHNS-------HDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAE 158
            ::||..:.::||...:.       ..|||||||||||||:.:|||:.:.:|.|||:|||||||..
 Frog    33 SSPTPGATASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKR 97

  Fly   159 WKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLNKSPVPGGGGGGGGGGANGGVNAG 223
            ||.|.:|.|.|||.||:|||..||.::||||||||:|.|:               ||:..|..|.
 Frog    98 WKQLKDGDKIPFIREAERLRLKHMADYPDYKYRPRKKVKS---------------GGSKPGDKAC 147

  Fly   224 GA--GNSGPSGPGSVGSPKDMQPQLSPLGQSL---PH------LHGHPHQSPYQSHPHHPHPHPH 277
            |:  |:|.|:|....|.|    |.....|..|   ||      ....|.|.|  ..|.|     |
 Frog   148 GSPGGSSSPTGSTGSGKP----PVKKSSGTKLCNKPHTKLVLGARAFPEQQP--CIPDH-----H 201

  Fly   278 HVQLAAATLSAK---------YGFGSPLELSLPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAG 333
            .:..:....|.:         |.||.......|.:.        .|..|||:   .:..:|....
 Frog   202 SLYKSRTAASGRQEKKPKHRVYIFGGAGYQGSPSVA--------VPASPTLS---SSSAEASDPL 255

  Fly   334 SIYHPWRYLPLISPETP---------PSP-PSSSGTGISSYGCVKSEKSSPNAVVASAASPPN-- 386
            |:|.........||.:|         .|| ||:|.:..||     |..|||::..:|::|...
 Frog   256 SLYEDGSGSAQNSPGSPSEHDGYTRASSPAPSTSHSSSSS-----SAASSPSSASSSSSSSDEEL 315

  Fly   387 -----IIXPTP--LRFGAGTSSSA 403
                 .: |:|  .....|:.|||
 Frog   316 EDELLELNPSPGFENMSLGSFSSA 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	51/78 (65%)
sox4	NP_001039084.1	HMG-box_SoxC	59..134	CDD:438838	50/74 (68%)