Protein Alignment Sox21a and sox12

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001025449.3
• Gene: sox12 / 562381
• ZFINID: ZDB-GENE-040724-33
• Length: 369
• Species: Danio rerio
• Alignment Length: 287
• Identity: 90/287 - (31%)
• Similarity: 125/287 - (43%)
• Gaps: 74/287 - (25%)

  Fly   120 HIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKE 184
            |||||||||||||:.:|||:.:..|.|||:|||||||..||||.:.:|.|||.||:|||..||.:
Zfish    66 HIKRPMNAFMVWSQIERRKIMEQWPDMHNAEISKRLGKRWKLLPDYEKIPFIKEAERLRLKHMAD 130

  Fly   185 HPDYKYRPRRKPK------------TLNKSPVPGGGGGGGGGG-----ANGGVNAGGAGNSGPSG 232
            :||||||||:|.|            ..:..|:||...|....|     |:.......:.|...|.
Zfish   131 YPDYKYRPRKKSKGSTPVKLGEKLPMKSSKPLPGRSSGLSCKGLKIKPASSKHKMNFSSNKYKSY 195

  Fly   233 PGSVGSPKDMQPQL-SPLGQ-----SLPHLHGHPHQSPYQSHPHHPHPHPHHVQLAAATLSAKYG 291
            ..|:.....|...| ||:.|     :..|...| .|:..||....|.|.
Zfish   196 SESMSDDDTMDVNLESPVTQQDDRNTSSHFVLH-QQATVQSEDQQPIPE---------------- 243

  Fly   292 FGSPLELSLPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAGSIYHPWRYLPLISPETPPSPPSS 356
                |.:.:|                   :...:.:|::.:.|....:       ||:..|.|..
Zfish   244 ----LRVKVP-------------------ISQTSSIQSLSSDSECQAF-------PESTTSEPRG 278

  Fly   357 SGTGISSYGCVKSEKSSPNAVVASAAS 383
            |.:|.||    ....:|.:::|:||.|
Zfish   279 STSGRSS----TPTSTSSSSLVSSACS 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	52/89 (58%)
sox12	NP_001025449.3	None