Protein Alignment Sox21a and sox2

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_998869.1
• Gene: sox2 / 407873
• XenbaseID: XB-GENE-484553
• Length: 311
• Species: Xenopus tropicalis
• Alignment Length: 291
• Identity: 128/291 - (43%)
• Similarity: 153/291 - (52%)
• Gaps: 70/291 - (24%)

  Fly   102 AP--TSHSNSNTGSHH---NSHDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKL 161
            ||  .|..|||:||::   ||.|.:||||||||||||||||||||:|||||||||||||||||||
 Frog    13 APQQASGGNSNSGSNNQSKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKL 77

  Fly   162 LTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTL---NKSPVPGGGGGGGGGGANGGVNAG 223
            |:|.:|||||||||||||||||||||||||||||.|||   :|..:|||....|......||.|.
 Frog    78 LSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGANPMTSGVGAS 142

  Fly   224 -GAG-----------NSGPSGPGSVGSPKDMQPQLSPLGQSLPHLHGHPHQSPYQSHPHHPHPHP 276
             |||           |...:|...:     ||.||           |:| |.|..|..:.|...|
 Frog   143 LGAGVNQRMDTYAHMNGWTNGGYGM-----MQEQL-----------GYP-QHPGLSAHNAPQMQP 190

  Fly   277 HH------VQLAAATLSAKYGFGSPLELSLPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAGSI 335
            .|      :|..:.:.|..|..||| ..|:.......||::               |.:|  ||:
 Frog   191 MHRYDVSALQYNSMSSSQTYMNGSP-TYSMSYSQQGAPGMS---------------LGSM--GSV 237

  Fly   336 YHPWRYLPLISPETPPSPPSSSGTGISSYGC 366
                     :..|:..|||..:.:..|...|
 Frog   238 ---------VKSESSSSPPVVTSSSHSRAPC 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	71/78 (91%)
sox2	NP_998869.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40		12/26 (46%)
		HMG-box_SoxB	35..114	CDD:438790	71/78 (91%)
		SOXp	106..194	CDD:463537	34/104 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	232..259		8/37 (22%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P41225	266..274