Protein Alignment Sox21a and Sox1

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_033259.2
• Gene: Sox1 / 20664
• MGIID: 98357
• Length: 391
• Species: Mus musculus
• Alignment Length: 393
• Identity: 151/393 - (38%)
• Similarity: 182/393 - (46%)
• Gaps: 89/393 - (22%)

  Fly    88 MHQHTHHHGNSHHNAPTSHS--------------NSNTGSHHNSHDHIKRPMNAFMVWSRGQRRK 138
            |...|..|......|||:.|              ....|....:.|.:|||||||||||||||||
Mouse     4 MMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGTKANQDRVKRPMNAFMVWSRGQRRK 68

  Fly   139 MAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTL---N 200
            |||:||||||||||||||||||:::|.:|||||||||||||||||||||||||||||.|||   :
Mouse    69 MAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKD 133

  Fly   201 KSPVPGG----GGGGGG-----------------------GGANGGVNAGGAGNSGPSGPGSVGS 238
            |..:.||    |.||||                       |||.||..|...|.:..:.||||.:
Mouse   134 KYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAA 198

  Fly   239 PKD----MQPQLSPLGQSLPHLHG-HPHQSPYQSHPHHPHPHPHHVQ---------LAAATLSAK 289
            ...    ||......||. |...| |||..|...||||||.|||:.|         |..:.:|..
Mouse   199 AAAAAAMMQEAQLAYGQH-PGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNS 262

  Fly   290 YGFGSPLELSLPRLP-------NAFPGLAHYPLDPTLALDLQARLQAMYAGSIYHPWRYLPLISP 347
            .|:.|........:|       .|..|.||    ...|:...|...|..:|::   .....|:..
Mouse   263 QGYMSASPSGYGGIPYGAAAAAAAAAGGAH----QNSAVAAAAAAAAASSGAL---GALGSLVKS 320

  Fly   348 E---TPPSP-------PSSSGTGISSYGCVKSEKSSPNAVVASAASPPNIIXPTPLRF---GAGT 399
            |   :||:|       |......||.| ....|...|.|..|:||.  :.:...|..:   |||.
Mouse   321 EPSGSPPAPAHSRAPCPGDLREMISMY-LPAGEGGDPAAAAAAAAQ--SRLHSLPQHYQGAGAGV 382

  Fly   400 SSS 402
            :.:
Mouse   383 NGT 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	69/78 (88%)
Sox1	NP_033259.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		9/47 (19%)
		HMG-box_SoxB	49..128	CDD:438790	69/78 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..249		18/35 (51%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P41225	342..350		3/8 (38%)