Protein Alignment Sox21a and sem-2

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_740846.1
• Gene: sem-2 / 172162
• WormBaseID: WBGene00004771
• Length: 404
• Species: Caenorhabditis elegans
• Alignment Length: 408
• Identity: 118/408 - (28%)
• Similarity: 161/408 - (39%)
• Gaps: 146/408 - (35%)

  Fly    66 PPPMPP---ADLAVPPAAPTPVAPK--------MHQHTHHH------GNSHH------NAPTSHS 107
            |..|||   |..|:..|:.|..|..        ..|...||      |...|      .:.|.:|
 Worm    17 PHMMPPINWAAAAIAVASSTSGATNATSSNSVATSQQLQHHPYGTAAGGYKHAQQAIPKSVTPYS 81

  Fly   108 NSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFID 172
            ::.  :...|.:|||||||||||||:.:|||:.:..|.|||:||||:||:.|:.||:.:|.||:.
 Worm    82 DAT--NCKKSSNHIKRPMNAFMVWSQMERRKICEHQPDMHNAEISKQLGSRWRSLTDEEKAPFVA 144

  Fly   173 EAKRLRALHMKEHPDYKYRPRRKPKTLNKSPVPGGGGGGGGGGANGGVNAGGAGNSGPSG----P 233
            ||:|||..||:|:|||||:||:|||                              ..|.|    |
 Worm   145 EAERLRVCHMQEYPDYKYKPRKKPK------------------------------KNPDGTLQQP 179

  Fly   234 GSVGSPKDMQPQLSPLGQSLPHLH-----------------------------GHPHQSPYQSHP 269
            ....:|:  |.|..|.|.| |...                             |:.|.|..|..|
 Worm   180 AQPQAPQ--QQQAPPRGAS-PQARQRKRPNTDQQSETQQFQNFKSVKVEQDWMGNAHMSHAQKMP 241

  Fly   270 HHP-HPHPHHVQLAAATLSAKYGF----------------------GSPLELSLPRLPNAFPGLA 311
            .|| :|.|.  :...|.|:.:.||                      ||||.::
 Worm   242 FHPSYPSPS--EFGHAPLTPESGFYDDYFTQQHHQQHFASQHHNSAGSPLRMT------------ 292

  Fly   312 HYPLDPTLALDLQARLQAMYAGSIY----HPWRYLPLISPETPPSPPSSSGTGISSYG-CVKSEK 371
                  .|.:|:....|.|...|.:    ||: ||....|........|..:|.|.|. |..||:
 Worm   293 ------NLGMDMGMPPQMMGHNSGFGAGNHPF-YLHTSPPSVDQDDMRSLSSGSSGYADCSASEQ 350

  Fly   372 --SSPNA----VVASAAS 383
              ||||:    .:|:||:
 Worm   351 STSSPNSAGVVTMATAAT 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	49/78 (63%)
sem-2	NP_740846.1	HMG-box_SoxC	92..159	CDD:438838	40/66 (61%)