Protein Alignment Sox21a and Hmg20b

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001415470.1
• Gene: Hmg20b / 15353
• MGIID: 1341190
• Length: 415
• Species: Mus musculus
• Alignment Length: 434
• Identity: 85/434 - (19%)
• Similarity: 117/434 - (26%)
• Gaps: 184/434 - (42%)

  Fly    95 HGNSHHNAPTSHSNSNTGSHH-------------NSHDHIKRPMNAFMV----WSRGQRRKMAQD 142
            ||.....|.|:.:...|...|             .|....|.|.....|    |.:|::||....
Mouse     3 HGPRQPGAATAPAGGKTPGQHGAFVVAVKQERSEGSRAGEKGPQEEEPVKKRGWPKGKKRKKILP 67

  Fly   143 N------------------------PKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMK 183
            |                        |.:...||:|.|||||..|...:|:.::|||::.:..::|
Mouse    68 NGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPAEKQRYLDEAEKEKQQYLK 132

  Fly   184 EHPDYK----YRPRRKPKTLNKSPVPGGGGGGGGGGANG--GVNAGGAG--------------NS 228
            |...|:    |:...:....||........|......||  ||:..|..              |.
Mouse   133 ELWAYQQSEAYKVCTEKIQENKIKKEDSSSGLMNTLLNGHKGVDCDGFSTFDVPIFTEEFLDQNK 197

  Fly   229 GPSG----------------------PGSVGSPKD---------------MQPQLSPLGQ----- 251
            ....                      ..|:.|.::               :|.||..:.|
Mouse   198 AREAELRRLRKMNVAFEEQNAVLQRHTQSMSSARERLEQELALEERRTLALQQQLQAVRQALTAS 262

  Fly   252 --SLP------------------HLHGHPHQSPYQSHPHHPHPHPHHVQLAAATL---------- 286
              |||                  .|||...:.|.|           |.:|.|...
Mouse   263 FASLPVPGTGETPTLGTLDFYMARLHGAIERDPAQ-----------HERLIARVKEILARRAPVT 316

  Fly   287 -------------SAKYGFGSPLELSLPRLPNAFPGLAHYPLDPTLALDLQARLQAMYAGSIY-- 336
                         ...|..|||....:...|:.|      ..:|...|.....|.|...||.|
Mouse   317 DLLDQEMPLPTRPERSYTLGSPGPPQMKSQPHPF------SFEPHPRLQRPGDLPASQGGSHYSG 375

  Fly   337 ----HPWRYLPLISPETPPSP-----------PSSSGTGISSYG 365
                .|   .||.| :|||.|           |.|.||..:..|
Mouse   376 SGTEEP---RPLDS-DTPPPPLVLSRRTPGRSPYSQGTCCAGAG 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	26/110 (24%)
Hmg20b	NP_001415470.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		15/67 (22%)
		HMG-box_HMG20B	69..152	CDD:438834	18/82 (22%)
		DAHL	<213..330	CDD:466085	17/127 (13%)