Protein Alignment Sox21a and HMG20B

DIOPT Version :10

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_006330.2
• Gene: HMG20B / 10362
• HGNCID: 5002
• Length: 317
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 41/184 - (22%)
• Similarity: 62/184 - (33%)
• Gaps: 42/184 - (22%)

  Fly    68 PMPPADLAVPPAAPTPVAPKMHQHTHHHG-------------------NSHHNAPTSHSNSNTGS 113
            |..|...|.|.....|         ..||                   .||...|........|.
Human     5 PKQPGAAAAPAGGKAP---------GQHGGFVVTVKQERGEGPRAGEKGSHEEEPVKKRGWPKGK 60

  Fly   114 HHNS--HDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKR 176
            ....  .:..|.|:..::.:...:|.::...:|.:...||:|.|||||..|...:|:.::|||:|
Human    61 KRKKILPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPTEKQRYLDEAER 125

  Fly   177 LRALHMKEHPDYKYRPRRK-------PKTLNKSPVPGG-----GGGGGGGGANG 218
            .:..:|||...|:.....|       .|.:.|.....|     ..|..||..:|
Human   126 EKQQYMKELRAYQQSEAYKMCTEKIQEKKIKKEDSSSGLMNTLLNGHKGGDCDG 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	23/85 (27%)
HMG20B	NP_006330.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		11/74 (15%)
		HMG-box_HMG20B	69..147	CDD:438834	23/77 (30%)