DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8100 and CG7320

DIOPT Version :9

Sequence 1:	NP_001261825.1	Gene:	CG8100 / 39565	FlyBaseID:	FBgn0036410	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_649034.3	Gene:	CG7320 / 40010	FlyBaseID:	FBgn0036782	Length:	646	Species:	Drosophila melanogaster

Alignment Length:	707	Identity:	175/707 - (24%)
Similarity:	275/707 - (38%)	Gaps:	195/707 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 DRQYFLLNLLIQVHKPLLHEELITMGSQLNDDPDS---YKEGTWRYIKDFR--ERVHQNRVPGPF 101
            ::|.|||.:|..|::||::|:...:|.||..|.:.   |.|...|:.:||.  :.:|:|
  Fly    30 EKQRFLLEILHHVNEPLMNEQWRLLGKQLVTDKEQYVVYNEQMTRFYEDFSLGKLLHRN------ 88

  Fly   102 VILNQLDEEMPLNLLGIYRFLTMAVDWTSFQRNACFARIHFHPLLFVNALQMAVEEREDTKDLRM 166
            |..|.|..:....:||:|:|...|.||.:..:|..:||:|.||.:||.||...:.:|||.:.|.|
  Fly    89 VRYNPLYADHYRQMLGLYQFFYNARDWYTLWQNISWARVHVHPCIFVQALTQLILKREDYQALIM 153

  Fly   167 PAMYEVLPQLYFEKEVILTA-----------------QEVTWNQLSPIRLVTPKRRWIDILLGYR 214
            |.:||:.|:.|.:...:..|                 :|:...:|.|:.|....|..|:......
  Fly   154 PKIYELWPESYHDDVTVRKARNFNFANWIRYVNMTDVEEIHPQKLEPLNLEGNLRGTIEWFQAMA 218

  Fly   215 NPKQPWMEEEPIPTDPLIIDNARKVAYLSLDLELNSHWNSLITRLIISIEEGKEKTNEPIIIDGD 279
            :.....|.|:         ....|:.:|..|::..|:|.:|...:|::.|            :.|
  Fly   219 DVNILRMNEQ---------KKRNKLEHLLEDIDWQSYWYNLNMGVILTAE------------NSD 262

  Fly   280 RLVAFRGSFDEVNFKKHLALGSHFHNTKLYLYNLHQFVAALSMEDLATGQKSTELIYPPLMTTGG 344
            :|                        .:...|.|.|.:|...:|  ..|||
  Fly   263 QL------------------------REWCYYQLSQILARYKLE--CYGQK-------------- 287

  Fly   345 VPYKGTSLNIEAVRGI------IDLTIDGLKDKIEMAVKHNNHAMDNLSIAGGIIGNNYLHICRQ 403
            :.||..:.|    |||      |...|..|:.|:...:...:..:.|.|.......||:|....:
  Fly   288 MAYKRLTQN----RGINEEFQFITKKISELEAKVGDTISFQSIQLTNGSRINLNENNNWLIGLEE 348

  Fly   404 L------NLAVNGQGINQPSMLGSATSNLRDPIYRSLLFRIY--DLLKSY---------ENENIF 451
            |      .|||: :.|....:|...|      |.||..|..|  .||.||         .|:..|
  Fly   349 LFPYDWTQLAVD-EVIETNILLDIRT------IVRSEDFYYYAERLLDSYRWYRQVFQPNNQKTF 406

  Fly   452 --PDVGGRETPKIVDIQVSRLVTFEETMTTDLINLI-DQQLLLSHRNNLQFLRRNLVARQHRLNH 513
              .|:      :|.|:|::.|:|:::.:..|:.|:: .|...|:.:....|   .|..||.||.|
  Fly   407 IPSDL------RIDDMQITPLITYDQPVDVDISNILAAQHFYLAGQFVWPF---TLQHRQFRLQH 462

  Fly   514 DPFSIGLDIVAPENLVVEARMYLSLPN-----QLRLRLHLDSFKCSLKRGLNHFERQFPTAISKP 573
            ..||..|.|.:.:......|::|:...     |......||||...:..|||...|:     ||.
  Fly   463 KDFSYNLLISSNKTQSTIFRVFLTTSERGGNIQREPFYQLDSFLTVIYPGLNRITRE-----SKE 522

  Fly   574 ---------TLSELY---------EADYASTDVTTSNRFPPHLQLPR-GTGDGLKLQLLV----- 614
                     :.:|||         |.|:.....|.:..||..|.||| |.|:.|||:||:
  Fly   523 FKGLAGDHISYTELYQFVKLAERDEFDFPLNISTANCAFPRRLILPRGGLGNPLKLRLLIVASVY 587

  Fly   615 --------EL--------SEWNGLESHF--------DGASVTVLAKTL--KDVIIFH 645
                    ||        |.|:.|...:        |..:|.:....:  |||.|.|
  Fly   588 DFRARQENELNCDFSQGVSRWDELPLGYPFERFLEDDALAVEISGDHVFWKDVHILH 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8100	NP_001261825.1	Hemocyanin_N	41..163	CDD:281684	43/125 (34%)
CG8100	NP_001261825.1	Hemocyanin_C	444..>621	CDD:281685	61/233 (26%)
CG7320	NP_649034.3	Hemocyanin_N	28..149	CDD:281684	43/124 (35%)
		Hemocyanin_M	157..>282	CDD:278784	27/169 (16%)
		Hemocyanin_C	400..644	CDD:281685	66/257 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28IXN
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0012705
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11511
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840