Protein Alignment Nprl3 and nprl-3

DIOPT Version :10

• Sequence 1: NP_648680.2
• Gene: Nprl3 / 39550
• FlyBaseID: FBgn0036397
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_501396.1
• Gene: nprl-3 / 185331
• WormBaseID: WBGene00018072
• Length: 511
• Species: Caenorhabditis elegans
• Alignment Length: 615
• Identity: 149/615 - (24%)
• Similarity: 253/615 - (41%)
• Gaps: 146/615 - (23%)

  Fly     9 AVILVYFDSKGDRLLYRYPYQTLGQTEVANDEQRKSRKRNP-YAVANTDDLLQTPTH-LGAAKSQ 71
            ||:.......|::::..||::.......:.|.|..|  .|| ..|......::.|:: .|...::
 Worm    16 AVMCFLTGQSGEKIVSIYPHRKPATKAPSKDPQPSS--SNPGQCVKPVLTSVKDPSYGFGRVDTE 78

  Fly    72 GQLQ-GFADEVLSALFAVKPQLCNQKFELKLNDVRFVSHPTLIPQKEQRSGPMAKQQMLINIVFA 135
            ..:. |    :|:.:|..:...||..|::|:|:.|||::    |:..:..|.....|  |:||||
 Worm    79 FDMSLG----MLAYVFKTQEIACNDGFDMKINNQRFVAY----PKTWKARGESTNYQ--ISIVFA 133

  Fly   136 LHAQASYSIVKCYHELSKRLGLALKFEEQRSGYLTEQTAQMARTHDEQQQQPLERTLELIAERCS 200
            |...........|..||.::.::|...:...|:|..:........:..:..|||.    .|:...
 Worm   134 LKNGCEQHTASAYQTLSNKIAVSLVMLQNYFGFLEREDKWADNAEEPNKDHPLEE----FAKTSF 194

  Fly   201 LAQALRSIFHDLCTTGLLSTSLNHNLTLCFCLPAKAHQLHK-----KGSMVDPETIDRCLRALKP 260
            :.|.|..:|.::...|.:...|.:.:.|.||  .:||.|.|     ||.    :.||..:|.:||
 Worm   195 IVQPLAEMFEEVRNRGNIHKYLINFVELGFC--DEAHALTKLNVVPKGR----QEIDEIVRKMKP 253

  Fly   261 YHGMLLLVDFAELLDCVPPTGARMLWQLVDVYDPLISLQSMSSNADLSIEHVYKLVSHLVYWAKA 325
            |||:|||.|.....|..|     ::.:|:....|..|:..||:.:.:.|..|:.::.||:.|.:|
 Worm   254 YHGILLLEDVWPTPDANP-----IVAKLLSHCSPDRSILDMSTASGIPIFEVFMIIRHLLQWTRA 313

  Fly   326 TIIYPLCETNVYVIAPD-APLHTKSHLVEKFSARFAG-MSLFEVISDFSLPTSIG---HLTTPLQ 385
            .:|||||.||:|..|.. .||   ..:.|||:|:|.. :.|...::.|:.|.::.   ....||.
 Worm   314 ILIYPLCNTNIYTSATSPQPL---DKMAEKFTAQFGNTIHLAAGLAHFNPPKTLDTFIRKNLPLH 375

  Fly   386 QPARQGILAQMVIWMLQHHLLMQLHTY--------VQFMPSEDEFGDSASCSNHLRDAISDEEGD 442
            :   ||:.|::|:.:|:|.:|||||.:        :..:|...|
 Worm   376 E---QGVRAKLVVALLRHQMLMQLHQFYYILKPYSIAILPEPKE--------------------- 416

  Fly   443 QEPDADELHGSMLSMSSHPLPVPAVLVGGHRREASE--DHSSLASDNIAVQPSSSHKSNFSITAS 505
                                |.||        |.::  :.|:|.:|                ...
 Worm   417 --------------------PCPA--------EFTKIIEESTLPND----------------VKG 437

  Fly   506 MSTDNCDSLDSMEDEQKLKELLQVFSDADRAAIRRIPASANVDDLSLLVKLYQMGYFKSEHHLEE 570
            :..|.|            .|:|:..|   .|:::|        .|||.||:..|  ....|||||
 Worm   438 VVADIC------------AEMLETTS---YASVKR--------TLSLFVKVAPM--MDGNHHLEE 477

  Fly   571 IMYFENLRRSQLLQLLDKFRDVLIIYETED 600
            |.|..||.|:::..:...|:.|:..:...|
 Worm   478 IKYKNNLDRTEIEGVFVSFKLVIATFRRPD 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nprl3	NP_648680.2	NPR3	76..413	CDD:451662	101/354 (29%)
nprl-3	NP_501396.1	NPR3	<251..402	CDD:451662	54/161 (34%)