Protein Alignment CG10171 and TMEM19

DIOPT Version :10

• Sequence 1: NP_729888.1
• Gene: CG10171 / 39501
• FlyBaseID: FBgn0036353
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_060749.2
• Gene: TMEM19 / 55266
• HGNCID: 25605
• Length: 336
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 148/327 - (45%)
• Similarity: 227/327 - (69%)
• Gaps: 12/327 - (3%)

  Fly     7 VLFCGLSVPISLFMWLGNVALSKFWSSDFEGYPTESRVIPPVRWLFSTLAPLALMTVALRRRSVN 71
            ::...|.:.|||..|:.::..|.::.:        .|.|.|.|||||.:.|:.:::..|:::|::
Human    19 IVILSLIICISLAFWIISMTASTYYGN--------LRPISPWRWLFSVVVPVLIVSNGLKKKSLD 75

  Fly    72 RSGAALGILVAFILSIASHPFFASLVVFFFSSSRATKFRAHMKRRFESDFREGEGQRNWIQVLCN 136
            .|||..|::|.|||:||:..||.||::||.|||:.||::..:|:|.:|:::|| |||||:||.||
Human    76 HSGALGGLVVGFILTIANFSFFTSLLMFFLSSSKLTKWKGEVKKRLDSEYKEG-GQRNWVQVFCN 139

  Fly   137 GGMAAQLALLYLLDCGSGERAVDFAREYRSSWLGVAVMSAFACCNGDTWSSELGSVLSQRDPVSI 201
            |.:..:|||||:::.|.||..|||:::|.:||:.:::::|.||..||||:||:|.|||:..|..|
Human   140 GAVPTELALLYMIENGPGEIPVDFSKQYSASWMCLSLLAALACSAGDTWASEVGPVLSKSSPRLI 204

  Fly   202 ITWRRVPRGTNGGVSLLGVAVSLLGGLLVGFGYFVTVRYTVEAKMLLISPPQWPIIAFGGIAGLF 266
            .||.:||.||||||:::|:..|||||..||..||:|  ..:....|.||.||||||||||:|||.
Human   205 TTWEKVPVGTNGGVTVVGLVSSLLGGTFVGIAYFLT--QLIFVNDLDISAPQWPIIAFGGLAGLL 267

  Fly   267 GSLLDSVLGGLLQFSGINEE-GKIVDTPGKGVRHVSGLRILDNHSVNLISSIVTGVTIPLLAQRF 330
            ||::||.||..:|::|::|. |.:|::|....||::|..||||::|||.||::..:.:|..|..|
Human   268 GSIVDSYLGATMQYTGLDESTGMVVNSPTNKARHIAGKPILDNNAVNLFSSVLIALLLPTAAWGF 332

  Fly   331 WP 332
            ||
Human   333 WP 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10171	NP_729888.1	DUF92	55..320	CDD:460391	129/265 (49%)
TMEM19	NP_060749.2	DUF92	59..322	CDD:460391	129/265 (49%)