DRSC/TRiP Functional Genomics Resources

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Protein Alignment trn and LRRN1

DIOPT Version :10

Sequence 1:NP_001261796.1 Gene:trn / 39491 FlyBaseID:FBgn0010452 Length:751 Species:Drosophila melanogaster
Sequence 2:NP_065924.3 Gene:LRRN1 / 57633 HGNCID:20980 Length:716 Species:Homo sapiens


Alignment Length:420 Identity:115/420 - (27%)
Similarity:186/420 - (44%) Gaps:57/420 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 ANCPPGCQCD-----------DNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKI-KTIDSSIQF 80
            :.||..|.|:           .....|.|.:.:|..:|..|:...|.|:::||.| ||:|...|.
Human    30 SECPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSNLSSDTQVLLLQSNNIAKTVDELQQL 94

  Fly    81 YAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQISEL 145
            : .||.||.|.|:...|           :||.|             ..|:.:|.|:|..|||:|:
Human    95 F-NLTELDFSQNNFTNI-----------KEVGL-------------ANLTQLTTLHLEENQITEM 134

  Fly   146 HQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFL 210
            .......|..::||.:..|:|..:...||.||..|..|:|:.|.|..: |...|.:.|:|..|.:
Human   135 TDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVI-DSRWFDSTPNLEILMI 198

  Fly   211 GMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLV 275
            |.|.:..|....|:.|..|..|.|.|..|.:|..::.:||..|..|...||:|.::|.:.|.|:.
Human   199 GENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVP 263

  Fly   276 RLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEV 340
            .|:.|.|.:|....|.||.|..:.:||.|.:|....|..|...|..:...|..|..::|..|..:
Human   264 NLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYI 328

  Fly   341 QEGALSGLSQLKHVVLKANALTSL----AEGLFPWKDLQTLDLSENPLSCDCRVMWLHNLLVAKN 401
            ...|...:..|:.::|..|||.::    .|.|   .:|:.:.:..|||.|||.:.|:       |
Human   329 HRLAFRSVPALESLMLNNNALNAIYQKTVESL---PNLREISIHSNPLRCDCVIHWI-------N 383

  Fly   402 ASQDDVS-----ELLCEFPERLRGESLRHL 426
            :::.::.     .:.|..|...:|..::.:
Human   384 SNKTNIRFMEPLSMFCAMPPEYKGHQVKEV 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trnNP_001261796.1 leucine-rich repeat 62..80 CDD:275380 8/18 (44%)
LRR 82..406 CDD:443914 94/327 (29%)
leucine-rich repeat 84..107 CDD:275380 7/22 (32%)
leucine-rich repeat 108..131 CDD:275380 4/22 (18%)
leucine-rich repeat 132..155 CDD:275380 8/22 (36%)
leucine-rich repeat 156..179 CDD:275380 8/22 (36%)
leucine-rich repeat 180..204 CDD:275380 7/23 (30%)
leucine-rich repeat 205..228 CDD:275380 7/22 (32%)
leucine-rich repeat 229..252 CDD:275380 8/22 (36%)
leucine-rich repeat 253..276 CDD:275380 8/22 (36%)
leucine-rich repeat 277..300 CDD:275380 8/22 (36%)
leucine-rich repeat 301..322 CDD:275380 7/20 (35%)
leucine-rich repeat 326..350 CDD:275380 5/23 (22%)
leucine-rich repeat 351..373 CDD:275380 7/25 (28%)
LRRCT 382..434 CDD:214507 11/50 (22%)
LRRN1NP_065924.3 LRRNT 32..75 CDD:214470 9/42 (21%)
leucine-rich repeat 54..73 CDD:275380 5/18 (28%)
LRR 1 73..95 9/21 (43%)
leucine-rich repeat 74..96 CDD:275380 9/22 (41%)
LRR <89..355 CDD:443914 85/291 (29%)
LRR 2 96..117 10/44 (23%)
leucine-rich repeat 97..120 CDD:275380 11/46 (24%)
LRR 3 120..141 7/20 (35%)
leucine-rich repeat 121..144 CDD:275380 8/22 (36%)
LRR 4 144..165 6/20 (30%)
leucine-rich repeat 145..168 CDD:275380 8/22 (36%)
LRR 5 168..189 7/21 (33%)
leucine-rich repeat 169..192 CDD:275380 7/23 (30%)
LRR 6 192..213 6/20 (30%)
leucine-rich repeat 193..216 CDD:275380 7/22 (32%)
LRR 7 216..237 6/20 (30%)
leucine-rich repeat 217..240 CDD:275380 8/22 (36%)
LRR 8 240..261 7/20 (35%)
leucine-rich repeat 241..264 CDD:275380 8/22 (36%)
LRR 9 264..285 8/20 (40%)
leucine-rich repeat 265..288 CDD:275380 8/22 (36%)
leucine-rich repeat 289..313 CDD:275380 7/23 (30%)
LRR 10 313..335 5/21 (24%)
leucine-rich repeat 314..335 CDD:275380 5/20 (25%)
LRR 11 338..359 5/20 (25%)
leucine-rich repeat 339..362 CDD:275378 7/25 (28%)
leucine-rich repeat 363..375 CDD:275378 4/11 (36%)
LRRCT 371..419 CDD:214507 11/50 (22%)
I-set 429..516 CDD:400151
Ig strand B 443..447 CDD:409562
Ig strand C 456..460 CDD:409562
Ig strand E 483..486 CDD:409562
Ig strand F 496..501 CDD:409562
Ig strand G 509..512 CDD:409562
FN3 531..600 CDD:214495
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 691..716
Blue background indicates that the domain is not in the aligned region.

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