Protein Alignment trn and let-4

DIOPT Version :10

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_510425.2
• Gene: let-4 / 181554
• WormBaseID: WBGene00002282
• Length: 773
• Species: Caenorhabditis elegans
• Alignment Length: 400
• Identity: 115/400 - (28%)
• Similarity: 189/400 - (47%)
• Gaps: 29/400 - (7%)

  Fly    29 NCPPG-----CQCDD--NTLVVQCGEGQLD-VLPIALNPSIQRLVIKS---NKIKTIDSSIQFYA 82
            |..||     |.|.:  :.:|:.|...... :|.|......|..:|:|   |:.:.::....|::
 Worm    19 NACPGVITQACFCSEVHSGIVLDCSNSSASGILQIIRTNQAQVGLIQSLTMNQAELVELPPNFFS 83

  Fly    83 ELTF--LDLSSNHLMTIPQRTFA-YQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQISE 144
            .|..  ||||.|.:..|....|| ....|:||.||||.|.::......||..:..|:|..|.|.|
 Worm    84 GLFIRRLDLSQNKIKKIDDAAFAGINPVLEEVVLNHNLIEKVPAAALAGLPNLLRLDLSNNSIVE 148

  Fly   145 L-HQGTFTPLLKIEELNLGENRIGYLDPKAFDGL-SQLRILYLDDNALTTVPDPVIFQAMPSLAE 207
            : .|..|..|.|:.::|||.|:|..:....|..: :.::.:.|..|.:|.||...| :.:..|..
 Worm   149 IQEQEIFPNLNKLYDINLGSNKIFSIHTSTFQNVKNSIQTINLGHNNMTAVPSSAI-RGLKQLQS 212

  Fly   208 LFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLS 272
            |.|..|.::.:.|..|.:|..|..|.|.|..:..::..:||.:..||.|.||.|::.::.:....
 Worm   213 LHLHKNRIEQLDALNFLNLPVLNLLNLAGNQIHELNRQAFLNVPSLRYLYLSGNKITKLTAYQFQ 277

  Fly   273 KLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKML 337
            ...:||.|.|..|:...|...:..|||||::|.: ...::..:.:.||: |.::..|.||||: |
 Worm   278 TFEQLEMLDLTNNEIGAIPANSLSGLKQLRQLYL-AHNKISNISSNAFT-NSSIVVLVLSSNE-L 339

  Fly   338 LEVQEGALSGLSQLKHVVLKANALTSLAEGLF-PWKDLQTLDLSENPLSCDCRVMWLH--NLLVA 399
            ..:..|.:|||..|:.|..:.|.:.::....| ....|..|||::|.|:......:|.  |||:.
 Worm   340 KTLTAGIISGLPNLQQVSFRDNQIKTINRNAFYDAASLVMLDLAKNQLTEIAPTTFLAQLNLLLV 404

  Fly   400 KNASQDDVSE 409
                  |:||
 Worm   405 ------DLSE 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	4/20 (20%)
		LRR	82..406	CDD:443914	98/331 (30%)
		leucine-rich repeat	84..107	CDD:275380	9/25 (36%)
		leucine-rich repeat	108..131	CDD:275380	10/22 (45%)
		leucine-rich repeat	132..155	CDD:275380	8/23 (35%)
		leucine-rich repeat	156..179	CDD:275380	6/23 (26%)
		leucine-rich repeat	180..204	CDD:275380	6/23 (26%)
		leucine-rich repeat	205..228	CDD:275380	7/22 (32%)
		leucine-rich repeat	229..252	CDD:275380	6/22 (27%)
		leucine-rich repeat	253..276	CDD:275380	6/22 (27%)
		leucine-rich repeat	277..300	CDD:275380	8/22 (36%)
		leucine-rich repeat	301..322	CDD:275380	4/20 (20%)
		leucine-rich repeat	326..350	CDD:275380	10/23 (43%)
		leucine-rich repeat	351..373	CDD:275380	4/22 (18%)
		LRRCT	382..434	CDD:214507	8/29 (28%)
let-4	NP_510425.2	leucine-rich repeat	66..86	CDD:275380	3/19 (16%)
		LRR	85..414	CDD:443914	100/333 (30%)
		leucine-rich repeat	88..111	CDD:275380	8/22 (36%)
		leucine-rich repeat	112..135	CDD:275380	10/22 (45%)
		leucine-rich repeat	136..160	CDD:275380	8/23 (35%)
		leucine-rich repeat	161..184	CDD:275380	6/22 (27%)
		leucine-rich repeat	186..209	CDD:275380	6/23 (26%)
		leucine-rich repeat	210..257	CDD:275380	13/46 (28%)
		leucine-rich repeat	258..281	CDD:275380	6/22 (27%)
		leucine-rich repeat	282..305	CDD:275380	8/22 (36%)
		leucine-rich repeat	306..328	CDD:275380	5/23 (22%)
		leucine-rich repeat	329..350	CDD:275380	8/21 (38%)
		leucine-rich repeat	353..400	CDD:275380	11/46 (24%)
		leucine-rich repeat	356..376	CDD:275380	3/19 (16%)
		leucine-rich repeat	401..419	CDD:275380	4/13 (31%)