DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cul6 and AT1G59800

DIOPT Version :9

Sequence 1:	NP_648620.1	Gene:	Cul6 / 39474	FlyBaseID:	FBgn0036332	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_176189.1	Gene:	AT1G59800 / 842273	AraportID:	AT1G59800	Length:	255	Species:	Arabidopsis thaliana

Alignment Length:	224	Identity:	44/224 - (19%)
Similarity:	90/224 - (40%)	Gaps:	61/224 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   479 RKLQSKAIIQLNNEL------SSGEITCHLN-QSVY-----ILEVSTLQMAVLMLFNRHERFTEQ 531
            |.::.::....|.|:      ::..|..:.| |.:|     ::|...:|..:..|..:|:....:
plant    25 RMIEGESEPAFNQEIMMMMHTATYRICAYKNPQQLYDKYRELIENYAIQTVLPSLREKHDECMLR 89

  Fly   532 ELVTALGVELETLQEALKQIKFLVYIEVNKVNYIEINMDFTNRK-----RRLFCN---EPLPRKM 588
            ||.......           |.||.:...::.|::.:  |.::|     |.:..|   :.:.|:|
plant    90 ELAKRWNAH-----------KLLVRLFSRRLVYLDDS--FLSKKGLPSLREVGLNCFRDQVYREM 141

  Fly   589 RKIEEKSEIEL--KIRRDKQVDAAIVR------IMKGQKQLEYSELISLVYEELKDRVKPQ--VS 643
            :.:..::.:.|  |.|..:|:|..:||      :..|...|:       .|||..:|:..|  .|
plant   142 QSMAAEAILALIHKEREGEQIDRELVRNVIDVFVENGMGTLK-------KYEEDFERLMLQDTAS 199

  Fly   644 FIKKR----------LDY-LVEREYLERD 661
            :...:          ||| |..::.|:|:
plant   200 YYSSKASRWIQEESCLDYTLKPQQCLQRE 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cul6	NP_648620.1	COG5647	25..670	CDD:227934	44/224 (20%)
		CULLIN	362..500	CDD:214545	4/26 (15%)
		Cullin_Nedd8	606..661	CDD:287520	17/73 (23%)
AT1G59800	NP_176189.1	Cullin	41..>255	CDD:279260	41/208 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1040292at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820