Protein Alignment: Cul6 and CUL1

• Sequence 1: NP_648620.1
• Gene: Cul6
• FlyBaseID: FBgn0036332
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001031575.1
• Gene: CUL1
• AraportID: AT4G02570
• Length: 738
• Species: Arabidopsis thaliana
• Alignment Length: 775
• Identity: 184/776 (24%)
• Similarity: 321/776 (41%)
• Gaps: 163/776 (21%)

  Fly     9 NYFDSMLPLIDNILQVVNQIFDDYTSFDGQKLMHLYHLIYKQCAAERNWNNPAQKNGRSLYIVLS 73
            :|..:.:..:..||:.:|:     .:||.::.|.||..||..|.     ..|.....:.||....
plant    13 DYMQTGITKLKRILEGLNE-----PAFDSEQYMMLYTTIYNMCT-----QKPPHDYSQQLYDKYR 67

  Fly    74 DCLMKRLKNIAWVMENQLDDNKPIRLIAKYLEHWVPYQRSCEKLNLACYHFNRNWVERERLKGDK 138
            :...:.:.:.......:..|...:|.:.|   .|..::.....|:...|:.:|.::.|..|.
plant    68 EAFEEYINSTVLPALREKHDEFMLRELFK---RWSNHKVMVRWLSRFFYYLDRYFIARRSLP--- 126

  Fly   139 ETYPIYRLAMISWKELVFEP--SVTILAAIRLI-------------------------LSQMPRE 176
               |:..:.:..:::||:..  |....|.|.|:                         :.||.|
plant   127 ---PLNEVGLTCFRDLVYNELHSKVKQAVIALVDKEREGEQIDRALLKNVLDIYVEIGMGQMER- 187

  Fly   177 YNKSLEYQVYQVLQSIVELYANDKYQDVSLPSRIDKI------FTEKVMDFYKSTT--------L 227
            |.:..|..:.|...|.....|:...|:.|.|..:.|.      ..|:|..:..|::        .
plant   188 YEEDFESFMLQDTSSYYSRKASSWIQEDSCPDYMLKSEECLKKERERVAHYLHSSSEPKLVEKVQ 252

  Fly   228 HEFQKIVVSNDYKDFKHFLRYACLAM----------------PEIENGTQFKA-ILKRYLAAR-- 273
            ||. .:|.::...:.:|   ..|.|:                .:|..|.:..| |.|:::.|.
plant   253 HEL-LVVFASQLLEKEH---SGCRALLRDDKVDDLSRMYRLYHKILRGLEPVANIFKQHVTAEGN 313

  Fly   274 -------------------LQETRLSGK-----DYIQAFLGLCRGPLQRALRDHTKLAEVVDAVC 314
                               :||..|..|     |....::..|   .|.....|..|.|..:..|
plant   314 ALVQQAEDTATNQVANTASVQEQVLIRKVIELHDKYMVYVTEC---FQNHTLFHKALKEAFEIFC 375

  Fly   315 KEEINRKGQIIDPTRLLVTYANELMTK---RQESEEAIIDELKRIVKCVEFLSDEYKFIDMYLKA 376
            .:.:.....    ..||.|:.:.::.|   .:.|:|||.|.|:::||.:.::||:..|.:.|.|.
plant   376 NKTVAGSSS----AELLATFCDNILKKGGSEKLSDEAIEDTLEKVVKLLAYISDKDLFAEFYRKK 436

  Fly   377 LRIRQINETSTSDGVESIMYSLLNKKMANFVTRCIYVQLRDVDKLRTLKKEFQDHLNSK-----G 436
            |..|.:.:.|.:|..|..:.:.|.::.....|..:...:.|:...|..:..|:|:|.|.     |
plant   437 LARRLLFDRSANDDHERSILTKLKQQCGGQFTSKMEGMVTDLTLARENQNSFEDYLGSNPAANPG 501

  Fly   437 IKLGF-----DFRPKCFKNDGSFENFNLTLPDELQQAWKEFRIFYEARKLQSKAIIQLNNELSSG 496
            |.|..     .|.|       |:::|::.||.|:.:..:.|:.|||.:....|    |....|.|
plant   502 IDLTVTVLTTGFWP-------SYKSFDINLPSEMIKCVEVFKGFYETKTKHRK----LTWIYSLG 555

  Fly   497 EITCHLN----QSVYILEVSTLQMAVLMLFNRHERFTEQELVTALGVELETLQEALKQI---KFL 554
              |||:|    |....|.|||.|.|||:|||..::.:..|::..|.:..|.|...|..:   |:.
plant   556 --TCHINGKFDQKAIELIVSTYQAAVLLLFNTTDKLSYTEILAQLNLSHEDLVRLLHSLSCAKYK 618

  Fly   555 VYIE------VNKVNYIEINMDFTNRKRRLFCNEPLPRKMRKIEEKSEIELKIRRDKQ--VDAAI 611
            :.::      |::.:..|.|..||:|.||:  ..|||    .::|:.::...:.:|::  :||||
plant   619 ILLKEPNTKTVSQNDAFEFNSKFTDRMRRI--KIPLP----PVDERKKVVEDVDKDRRYAIDAAI 677

  Fly   612 VRIMKGQKQLEYSELISLVYEELKDRVKPQVSFIKKRLDYLVEREYLERDNYY-NIYRYL 670
            |||||.:|.|.:.:|:|...|:|....||.:..||||::.|:.|:|||||... |::|||
plant   678 VRIMKSRKVLGHQQLVSECVEQLSRMFKPDIKAIKKRMEDLITRDYLERDKENPNMFRYL 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cul6	NP_648620.1	COG5647	25..670	CDD:227934	180/758 (24%)
		CULLIN	362..500	CDD:214545	37/148 (25%)
		Cullin_Nedd8	606..661	CDD:287520	27/57 (47%)
CUL1	NP_001031575.1	Cullin	34..640	CDD:279260	138/645 (21%)
		CULLIN	422..563	CDD:214545	40/154 (26%)
		Cullin_Nedd8	670..730	CDD:287520	28/60 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1040292at2759
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR11932
Phylome	0	0.000	Not matched by this tool.
	2	2.110