Protein Alignment Cul6 and Cacul1

DIOPT Version :10

• Sequence 1: NP_648620.1
• Gene: Cul6 / 39474
• FlyBaseID: FBgn0036332
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001402930.1
• Gene: Cacul1 / 365493
• RGDID: 1308127
• Length: 377
• Species: Rattus norvegicus
• Alignment Length: 234
• Identity: 50/234 - (21%)
• Similarity: 92/234 - (39%)
• Gaps: 51/234 - (21%)

  Fly   449 KNDGSFENFNLTLPDELQQAWKEFRIFYEARKLQS---KAIIQLNNELSSGE----ITCHLNQSV 506
            |.||:.:......|.:.      ..|.||  ::.|   |.:.|.::|....:    ||.||.:..
  Rat   147 KLDGAIDQLLTQSPGDY------IPISYE--QIYSCVYKCVCQQHSEQMYSDLIKKITSHLERVS 203

  Fly   507 YILEVSTLQMAVLMLFNRHERFTEQELVTALGVELETLQEALKQIKFLVYIEVNKVNYIE--INM 569
            ..|:.|...:.:       |||.     .|||..:..||..:.     ::|.:||. |||  :|.
  Rat   204 KELQASPPDLYI-------ERFN-----IALGQYMGALQSIVP-----LFIYMNKF-YIETKLNR 250

  Fly   570 DFTNRKRRLFCNEPLPRK-----MRKIEEKSEIELKIRRDKQVDAAIVRIMKGQKQL--EYSELI 627
            |..:...:|| .|.:..|     |..:.|......::     ..:.:..|:||...|  |:.::.
  Rat   251 DLKDDLIKLF-TEHVAEKHIYSLMPLLLEAQSTPFQV-----TPSTMANIVKGLYTLRPEWVQMA 309

  Fly   628 SLVYEELKDRVKPQVSFIKKRL-DYLVEREYLERDNYYN 665
            ..::.:....:.|..  ::..| :|..:.:.|:|:...|
  Rat   310 PTLFSKFIPNILPPA--VESELSEYAAQDQKLQRELIQN 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cul6	NP_648620.1	COG5647	25..670	CDD:227934	50/234 (21%)
Cacul1	NP_001402930.1	Cullin	145..>269	CDD:459983	37/148 (25%)