Protein Alignment CG42588 and gtf3c2

DIOPT Version :10

• Sequence 1: NP_648604.2
• Gene: CG42588 / 39457
• FlyBaseID: FBgn0260965
• Length: 2730
• Species: Drosophila melanogaster
• Sequence 2: XP_031757794.1
• Gene: gtf3c2 / 100497817
• XenbaseID: XB-GENE-997570
• Length: 931
• Species: Xenopus tropicalis
• Alignment Length: 1029
• Identity: 204/1029 - (19%)
• Similarity: 341/1029 - (33%)
• Gaps: 328/1029 - (31%)

  Fly  1798 SEDPEAV-EGDSVEVPIKRKASTRRGSVPRDTPISSVNASDESAVLESVPKKGRRSNISSVPADT 1861
            |:.|..| |..|.:..:...|..:|.:.|..:|          |:..|||:          |...
 Frog    79 SDSPVCVREEPSTQASLGCSAQAKRLNDPLSSP----------ALPASVPE----------PMSP 123

  Fly  1862 TIPKSSKSDSLNAIEIIPPICEEPKVVPSKRGRKRAAPSDIETGLAKKLKTEESSETERVVDFNL 1926
            |:|...::......::.|.:     .||.|||||..|
 Frog   124 TLPCLHENGPPTGSQLTPLV-----KVPKKRGRKSKA---------------------------- 155

  Fly  1927 RLLLIRKRDQLDTDEVLTNDGKGQGPLQCGLCLVRSDKNNWQRHIGEHYGVGWLVGETPKNITRS 1991
            .|||||:...||.:.:....           ..:|.:.:|..            :..||....|.
 Frog   156 ELLLIRQAQALDAEALARQS-----------LALRQESDNQD------------METTPSGRPRR 197

  Fly  1992 GIMTMMKNYLQKNGGKLTCRLCNHQLGSYLGMMLHLEGCGNKQRFQCEFCQRSYTKLSLPVHIRT 2056
            ........||             |.|...|                      |.:.||.|    |
 Frog   198 RAAKTALMYL-------------HDLADEL----------------------SSSGLSSP----T 223

  Fly  2057 CPKRIAPQVTEDPEDADGDCKETVFSNAGRAKRKSTIKAETKLKKIGEALTTQKSGEGASAKNDF 2121
            .|..:          :||...|     .|:::|:                  ::..||:.
 Frog   224 KPSAV----------SDGSSDE-----RGKSRRR------------------KRKAEGSE----- 250

  Fly  2122 DGDSSDYDLTKDKESSEEYDSEGVDSNEDSISSEGEGSLG----DNFST-SKQSKANRRGDIDRK 2181
              :.|||.:::|.....|::.|    :.:|:|...|..|.    ..||| .::|....||..|..
 Frog   251 --EDSDYVVSEDVLKEAEFEEE----DNESLSGAYEPELSTFRRKAFSTPGERSGPQIRGFADNG 309

  Fly  2182 RICNRPVNVGECQQKPLLSRYHHLEARATHKWNEFVQRNYEAGALFTQLVPS---YSKIPEKNTD 2243
              .:..:.|      |:....|     .|.::.:....::|    |...:||   :..:..:..:
 Frog   310 --FHNSIMV------PVWKASH-----VTAEYRDTCYSDWE----FPDWIPSTENWHFLTHREAE 357

  Fly  2244 GMLPPKN-TPSMRYSYGKVKNEDDWKQLAPFEGF---NKEGEYVGYLGSSIKKLEWVP-LPPKAA 2303
            ..||.:. :|........:|.|.....|..|:..   .:..:...::|..:..|||.| |....:
 Frog   358 PYLPAQRLSPPFTIRREGIKEEAKPCTLGRFQSLPPHPQRWDMNFFVGGPVWSLEWCPTLGGSGS 422

  Fly  2304 SQYLLCSVRSKMKTFARHKKLKDEDG------LLMLLKCTAKNAGKSWTLRPELHYCVHVPNGPI 2362
            .|||.......|..  |||    .||      ||.|......:...|....|...|.:.|.:|.|
 Frog   423 CQYLALYCHWGMDD--RHK----VDGVHPGPALLQLWSLGPLDMENSCDSGPVFSYGIAVDHGCI 481

  Fly  2363 HSFSFLPSGGYD------KSSN--RLGVLAVANSLSSVHIYALP-----LELANDEID-ENADEK 2413
            ....|.||||::      ||..  |||:||.|.|...:.||:||     ......::. ::..|.
 Frog   482 WDMKFCPSGGWELPCTSRKSLQMARLGLLAAAFSSGHIEIYSLPHPESLYSHRKSQVKAQDLWEH 546

  Fly  2414 VVIQLDSLITL---TLDINNPVQD-QCTKICWSLSAGHSFLATGYSSGHFALWDIGEKDNLNCFI 2474
            .|.::|.::.|   ::....|.:. ||..:.|..:..|.:||.|:..|..::||:..|..|.
 Frog   547 TVCKVDCVVRLQVGSIKACTPGESGQCFTLAWHPAKPHQYLAAGFYDGTVSIWDLKTKSVLQ--- 608

  Fly  2475 RNNQTHFVP----VNFLYIGE--RNVQYMDLHYDNNGPRWLAVGTSIRQFKIYDI---------- 2523
            |..|...:.    ::||....  |:|::...  |.|   :|....:.|:.|.:|:
 Frog   609 RVRQGRVIKQYPFLSFLSHDHAVRSVEWCKA--DGN---FLVTSGNDRRLKFWDLRRLPEPINNM 668

  Fly  2524 -------ANWSNPY---ILTQDTISSLYMANLTWSPICEALVVSSSHF-FRTIAVSP-------- 2569
                   .:|..||   .:.||   :.|.::    .:|....|.|... ::...|:|
 Frog   669 KRFQSTELSWLLPYSGVAVAQD---NCYASH----GLCGIHYVDSGFLGYKPYFVTPRKGTVWSV 726

  Fly  2570 SGIQFEHRTLDGTLTTTREMHTNCQQNHMVFVTDNGDLVFLDVRNLNCGPALLKSTVNS-----R 2629
            ||..:......|.:|                    |:::.:.:.|||.      ::||:     |
 Frog   727 SGSDWLSSIAAGDVT--------------------GEVIVIVLPNLNV------TSVNTKRPADR 765

  Fly  2630 AVSTTELHHLGSSAPSATDP-----------------IDPDEF---VRDYGLQINPLVPEPHKR- 2673
            .....:...|...:|.:|.|                 :.|..|   ...:||....:.....||
 Frog   766 RFPVYKADFLPHVSPESTQPGTELPAGPLAESSEWGHLKPKSFRAAAGRFGLLFQDMDMRDFKRL 830

  Fly  2674 ------KSTYLSAKRRPQNIHSLAMTRFNCVRCNWNSPTHTWVAMGAEHGMLRI 2721
                  |..:.:..:...|:..:.:...:.||.:.|..||.|||.|...|::||
 Frog   831 LSREPVKRMHANENKGDLNMERVQIEAVHKVRFSPNLDTHAWVASGGHSGLVRI 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42588	NP_648604.2	PHA03247	<11..541	CDD:223021
		WD40 repeat	2363..2403	CDD:293791	18/52 (35%)
		WD40 repeat	2437..2477	CDD:293791	11/39 (28%)
		WD40 repeat	2484..2533	CDD:293791	13/70 (19%)
		WD40 repeat	2541..2588	CDD:293791	10/55 (18%)
gtf3c2	XP_031757794.1	WD40 repeat	482..533	CDD:293791	18/50 (36%)
		WD40	<547..>659	CDD:475233	28/119 (24%)
		WD40 repeat	574..625	CDD:293791	12/53 (23%)
		WD40 repeat	631..664	CDD:293791	8/37 (22%)
		WD40 repeat	676..716	CDD:293791	9/46 (20%)
		WD40 repeat	724..754	CDD:293791	7/49 (14%)