Protein Alignment CG10973 and SIL1

DIOPT Version :10

• Sequence 1: NP_001034002.1
• Gene: CG10973 / 39447
• FlyBaseID: FBgn0036306
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: XP_011541872.1
• Gene: SIL1 / 64374
• HGNCID: 24624
• Length: 471
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 54/234 - (23%)
• Similarity: 103/234 - (44%)
• Gaps: 26/234 - (11%)

  Fly    68 NSEESSTDDQIESLDVIRSHIDDIDNAITLVKLGGTATLLRYITHSDSEVRESALNTVAEVAQNN 132
            ||..||.:::|.:|..:..::..:|||..|:..||...::..:..::..|:|.|...:.....:|
Human   203 NSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSN 267

  Fly   133 VFCQNALINDKFLPALAKNLSHSNPNTVRCS-LYAISSLIRNFQPGYDEFKRIKGIRSLIPCLKS 196
            ...|...|....|..|...|:...|.|.:.. |:|:.||:|:|.....:|.::.|::.|...::.
Human   268 PKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQE 332

  Fly   197 TNTNVY-VKTAFLIASLTSIEKSVRDDFVKEEVFPVLVENLKPVDDFDIKQETTLFALSSLSRES 260
            ..|.|. |:...|:..|.: ||.    |.:||.  .|.:.:.|.   .::|...:..|..|..:.
Human   333 KGTEVLAVRVVTLLYDLVT-EKM----FAEEEA--ELTQEMSPE---KLQQYRQVHLLPGLWEQG 387

  Fly   261 ELKLST--------EKREEILSKLQQIISKNKQSETCED 291
            ..:::.        :.||::|..|..:::      ||.|
Human   388 WCEITAHLLALPEHDAREKVLQTLGVLLT------TCRD 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10973	NP_001034002.1	Fes1	13..94	CDD:462534	7/25 (28%)
		armadillo repeat	97..128	CDD:293788	6/30 (20%)
		armadillo repeat	136..172	CDD:293788	11/36 (31%)
		armadillo repeat	178..209	CDD:293788	6/31 (19%)
SIL1	XP_011541872.1	None