Protein Alignment CG10973 and HSPBP1

DIOPT Version :10

• Sequence 1: NP_001034002.1
• Gene: CG10973 / 39447
• FlyBaseID: FBgn0036306
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: XP_005258758.1
• Gene: HSPBP1 / 23640
• HGNCID: 24989
• Length: 431
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 60/223 - (26%)
• Similarity: 104/223 - (46%)
• Gaps: 24/223 - (10%)

  Fly     7 PRGALSLQNVLK--YTVQHHDPNPEAAPKLETPDPERAQFLANALNAM---TVDAAAALKAALVI 66
            ||   :||.:|:  .|....:|:|...|..|    ||.|:|..|::|.   ..:....:|:.|.:
Human    42 PR---NLQGLLQMAITAGSEEPDPPPEPMSE----ERRQWLQEAMSAAFRGQREEVEQMKSCLRV 99

  Fly    67 LN-------SEESSTDDQIE---SLDVIRSHIDDIDNAITLVKLGGTATLL-RYITHSDSEVRES 120
            |:       .|.....||.|   :|:::....:::|||....:|.|...|: ||:....:.:|..
Human   100 LSQPMPPTAGEAEQAADQQEREGALELLADLCENMDNAADFCQLSGMHLLVGRYLEAGAAGLRWR 164

  Fly   121 ALNTVAEVAQNNVFCQNALINDKFLPALAKNLSHSNPNTVRC-SLYAISSLIRNFQPGYDEFKRI 184
            |...:...:||....|..::....|..|.:.|.....:|||. :|:|||.|:|..:.|..:|.|:
Human   165 AAQLIGTCSQNVAAIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRL 229

  Fly   185 KGIRSLIPCLKSTNTNVYVKTAFLIASL 212
            .|...|:..::.....:.||:|||:.:|
Human   230 DGFSVLMRAMQQQVQKLKVKSAFLLQNL 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10973	NP_001034002.1	Fes1	13..94	CDD:462534	23/95 (24%)
		armadillo repeat	97..128	CDD:293788	7/31 (23%)
		armadillo repeat	136..172	CDD:293788	12/36 (33%)
		armadillo repeat	178..209	CDD:293788	8/30 (27%)
HSPBP1	XP_005258758.1	Fes1	45..139	CDD:462534	25/97 (26%)
		armadillo repeat	88..130	CDD:293788	8/41 (20%)
		armadillo repeat	137..174	CDD:293788	8/36 (22%)
		armadillo repeat	180..215	CDD:293788	11/34 (32%)