Protein Alignment CG10984 and Ankrd11

DIOPT Version :10

• Sequence 1: NP_729823.2
• Gene: CG10984 / 39446
• FlyBaseID: FBgn0036305
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001074848.2
• Gene: Ankrd11 / 77087
• MGIID: 1924337
• Length: 2643
• Species: Mus musculus
• Alignment Length: 554
• Identity: 154/554 - (27%)
• Similarity: 251/554 - (45%)
• Gaps: 89/554 - (16%)

  Fly   147 SEHGKDVKGASLKLTSRVEKSSKLAATKGSPSGNKSSASNAEKEPAETSKNV--DIENETECSDD 209
            ::...||:..:.| .|.|..:.......|...|....|..||:.||...:..  .:..|.|.|::
Mouse  2135 AKDASDVEAEAAK-ASPVPPAESPPGPTGVLGGGDVPAPAAEEPPAPPPQEASPQLSTEPEPSEE 2198

  Fly   210 YKSNDSLYNGGLKVPPLKIVIPQQNCSIDTEGNVLRTGKVTASRNAALPYVVSSNSDSIDTVITN 274
                          |.|.:|:   ..:::||        |.|..:|.    .:|.|:|:......
Mouse  2199 --------------PKLDVVL---EATVETE--------VLADDSAP----EASISNSVPAPSPP 2234

  Fly   275 QSISP------HESPQKSNSICSTALDDKNIKLFNDEKNLRVLRSSHRTG-----VTSVERSSNN 328
            |...|      .|:...|.:.|...          |......|..:|.:.     |.:.|....|
Mouse  2235 QQQPPGGGDEEAETEDPSATPCCAP----------DGPTTDGLAQAHNSAEASCVVAAAEGPPGN 2289

  Fly   329 -----SSPQMQSSSPSPASSNHANDPADVKLSYSNMTSSPIPQGHQFDQEAITNVPSPSTSSTSS 388
                 :.|:.:.:|..|.:......|..:..:.:.|.:|...||    ..|....|.|:.:|.:.
Mouse  2290 VQAEATDPEPKPTSEVPKAPKVEEVPQRMTRNRAQMLASQSKQG----IPAAEKDPMPTPASRAK 2350

  Fly   389 SKDINPSNVEL-HPRKRKIR------PKNTDDSSKNSN--------AADSGVNSEESHPHDHPFT 438
            .:.....:.:. |||||:.:      .:..:.|::.:.        |....:..:...|:....:
Mouse  2351 GRASEEEDAQAQHPRKRRFQRSSQQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRS 2415

  Fly   439 NGFQMFLSIRRQIEKKWKSLYPVKPRPPQGYNEYLLTKKSYLL--RRNATISVPDI--PRTVPQA 499
            |.:..:|.||::||:|.|.|..:.|:.||.|.||:....||||  :..:.:.:|.|  |.::.:.
Mouse  2416 NPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEP 2480

  Fly   500 MERIYQDQEKARRDLIEAHTVEREKLCMNVEQEIIRVHSKAARSISGQPAPYSVCTYLKDDEVYN 564
            ::.:::.||..|..|...|::|||||.::.||||:|||.:|||:|:.|..|:|.||.|.|.||||
Mouse  2481 LKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYN 2545

  Fly   565 MITPEQDEKEKSARCRFNGRLLLSWLQDVDDKWEKIKESMVLRHHNEAESLHAVQVMDWNIFAK- 628
            |....|.::.||.|.|||.|..:|||||||||::::|..:::|..:||.:|:|||.|:|.:.|:
Mouse  2546 MPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKAQE 2610

  Fly   629 -----RNRLCDNPIEVNLEHVPIVSVGDDFDTLP 657
                 ...||.|  ||...:||:|.|.|||..||
Mouse  2611 LDPAGHKSLCVN--EVPSFYVPMVDVNDDFVLLP 2642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10984	NP_729823.2	None
Ankrd11	NP_001074848.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..90
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..170
		ANKYR	<158..>287	CDD:440430
		ANK repeat	167..198	CDD:293786
		ANK 1. /evidence=ECO:0000255	167..196
		ANK repeat	200..231	CDD:293786
		ANK 2. /evidence=ECO:0000255	200..229
		ANK 3. /evidence=ECO:0000255	233..262
		ANK repeat	233..261	CDD:293786
		ANK 4. /evidence=ECO:0000255	266..292
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	289..365
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..504
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	517..651
		PTZ00121	<666..1543	CDD:173412
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	727..805
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	918..962
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	977..1037
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1051..1074
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1114..1388
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1420..1711
		PHA03247	<1641..2160	CDD:223021	5/25 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1863..1900
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1981..2027
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2111..2386		55/294 (19%)
		PRK07003	<2143..>2367	CDD:235906	50/267 (19%)
		Important for protein degradation. /evidence=ECO:0000250|UniProtKB:Q6UB99	2349..2643		105/296 (35%)