Protein Alignment CG10984 and Ankrd12

DIOPT Version :10

• Sequence 1: NP_729823.2
• Gene: CG10984 / 39446
• FlyBaseID: FBgn0036305
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001101708.1
• Gene: Ankrd12 / 316775
• RGDID: 1310118
• Length: 2047
• Species: Rattus norvegicus
• Alignment Length: 683
• Identity: 179/683 - (26%)
• Similarity: 293/683 - (42%)
• Gaps: 141/683 - (20%)

  Fly    11 FNTGATQPRSNSNTPMSERQQMALLIQMTANSS----TVQSQSLELLLVGL-----NFNLHHSSR 66
            |...:.||.|.:|..:|:.:.:...:.::..:|    .:|.:|...::..:     ||.....|.
  Rat  1469 FTLSSPQPCSFTNQSLSDAESLPKPVSLSYGASQEPGVLQQRSAAHMISSVLESDNNFTKEVESS 1533

  Fly    67 TTLKKNECKKGDAETDEGSLNEKQEVLDTKDK--------SSAEESSNDGKSSDTNHQGTSAAKR 123
            ..|.  :.:|.::.....|.:..||.|...:|        |..:.|.:|..|....|...|  |.
  Rat  1534 FVLA--DIQKTNSFVPAYSESTVQETLPNFEKANTLLVLPSEKDFSGSDAASQLNTHYAFS--KL 1594

  Fly   124 CYSDIEEDYEESGEDVKKKKRKDSE---HGKDVKGASLKLTSRVEKSSKL-AATKGSPSGNKSSA 184
            .|........|.|.|       |::   |.|:.|..||.||...:..|.| ....|.|.||.:..
  Rat  1595 TYKSSSSHEIEKGPD-------DTQVISHEKENKLQSLVLTPLSKCDSDLYEVNAGMPKGNLNEQ 1652

  Fly   185 SNAEKEPAETSKNVDIENETECSDDYKSNDSLYNGGLKVPPLKIVIPQQNCSIDTEGNVLRTGKV 249
            .|.:..|       |.|.::..::|.:|                   ||:.....|.:
  Rat  1653 DNPKHGP-------DSEKDSLSTEDEES-------------------QQSTLSSVENH------- 1684

  Fly   250 TASRNAALPYVVSSNSDSIDTVITNQSISPHESPQKSNSICSTALDDKNIKLFNDEKNLRVLRSS 314
              |:.:|.|.:     ...|.::..:.....|..:..|........:|...|.:..|  :||
  Rat  1685 --SQQSAQPEI-----QKYDQMVKGELEENAEDDKTENQTPQRMTRNKASALVSQSK--QVL--- 1737

  Fly   315 HRTGVTSVERSSNNSSPQMQSSSPSPASSNHANDPADVKLSYSNMTSSPIPQGHQFDQEAITNVP 379
              .|.|.:....|:|||:                      ....:|....||.|...:..::.||
  Rat  1738 --AGCTLLPEKDNDSSPR----------------------GRIRLTEEDDPQIHHPRKRKVSRVP 1778

  Fly   380 SPSTSSTSSSKDINPSNVELHPRKRKIRPKNTDDSSKNSNAA--DSGVNSEESHPHDHPFTNGFQ 442
            .|        ..::||.::            ..:.::.|.||  || :..:|..|:.....|.:.
  Rat  1779 QP--------VQVSPSLLQ------------AKEKTQQSLAALVDS-LKLDEIEPYSSERANPYF 1822

  Fly   443 MFLSIRRQIEKKWKSLYPVKPRPPQGYNEYLLTKKSYLLRRN--ATISVPDI--PRTVPQAMERI 503
            .:|.||::||:|.|.|..|.|:.||.|:||:....||||..|  :.|.:|.|  |.::...::.:
  Rat  1823 EYLHIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLKEL 1887

  Fly   504 YQDQEKARRDLIEAHTVEREKLCMNVEQEIIRVHSKAARSISGQPAPYSVCTYLKDDEVYNM-IT 567
            ::.||..|..|...|::|||||.::.|||::|||.:|||:::.|..|:|.||.|.|.||||: :.
  Rat  1888 FRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYNVPLD 1952

  Fly   568 PEQDEKEKSARCRFNGRLLLSWLQDVDDKWEKIKESMVLRHHNEAESLHAVQVMDWNIFAKRNRL 632
            .:.|:.:.|.|.|||.|..:|||||||||::|:|..:::|..:||.:|:|||.::|.:  |...|
  Rat  1953 SQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQL--KLQEL 2015

  Fly   633 CDNP--------IEVNLEHVPIVSVGDDFDTLP 657
              :|        .|:...:||:|.|.|||:..|
  Rat  2016 --DPATYKSISIYEIQEFYVPLVDVNDDFELTP 2046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10984	NP_729823.2	None
Ankrd12	NP_001101708.1	ANKYR	<173..>291	CDD:440430
		ANK repeat	184..215	CDD:293786
		ANK repeat	217..248	CDD:293786
		ANK repeat	250..278	CDD:293786
		PTZ00121	<368..1011	CDD:173412
		PTZ00108	<916..1202	CDD:240271