Protein Alignment Klc and klc1a

DIOPT Version :10

• Sequence 1: NP_524049.1
• Gene: Klc / 39445
• FlyBaseID: FBgn0010235
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001429199.1
• Gene: klc1a / 393928
• ZFINID: ZDB-GENE-040426-1599
• Length: 647
• Species: Danio rerio
• Alignment Length: 509
• Identity: 353/509 - (69%)
• Similarity: 415/509 - (81%)
• Gaps: 13/509 - (2%)

  Fly     3 QMSQDEIITNTKTVLQGLEALRVEHVSIMNGI----------AEVQKDNEKSDMLRKNIENIELG 57
            ::||||::..|:.|:|||||||.||.:|:.|:          .|.:...||:.|:::::|.:|||
Zfish    23 KLSQDELLCRTREVMQGLEALRAEHQAILEGLMGTLRCLKQSQEGRAVEEKTAMIQRSMEMLELG 87

  Fly    58 LSEAQVMMALTSHLQNIEAEKHKLKTQVRRLHQENAWLRDELANTQQKFQASEQLVAQLEEEKKH 122
            ||||||||||:.||..:||||.||:.|||||.|||.|||||||.|||:.|.|||.||||||||||
Zfish    88 LSEAQVMMALSGHLSAVEAEKQKLRAQVRRLCQENQWLRDELAGTQQRLQKSEQSVAQLEEEKKH 152

  Fly   123 LEFMASVKKYDEN-QEQDDACDKSRTDPVVELFPDEENEDRHNMSPTPPSQF-ANQTSGYEIPAR 185
            ||||..:||||:: ...||....|..:.:.:|||||::|....:.|...|.. |.|..|||||||
Zfish   153 LEFMNQLKKYDQDLSPSDDKDSDSSRETLDDLFPDEQDEPGPGIQPPHSSAVAAAQQGGYEIPAR 217

  Fly   186 LRTLHNLVIQYASQGRYEVAVPLCKQALEDLERTSGHDHPDVATMLNILALVYRDQNKYKEAANL 250
            ||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||
Zfish   218 LRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAANL 282

  Fly   251 LNDALSIRGKTLGENHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALEIREKVLGKDHPDVAKQL 315
            |||||:||.||||.:||||||||||||||||||||||:|||||||||||||||||||||||||||
Zfish   283 LNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQL 347

  Fly   316 NNLALLCQNQGKYDEVEKYYQRALDIYESKLGPDDPNVAKTKNNLAGCYLKQGRYTEAEILYKQV 380
            |||||||||||||:|||.||||||:||::|||||||||||||||||.||||||::.:||.|||::
Zfish   348 NNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEI 412

  Fly   381 LTRAHEREFGAIDSKNKPIWQVAEEREEH-KFDNRENTPYGEYGGWHKAAKVDSPTVTTTLKNLG 444
            ||||||||||::|.:|||||..||||||. |...::.||:||||||:||.|||||||||||||||
Zfish   413 LTRAHEREFGSVDDENKPIWMHAEEREEQSKIKQKDGTPFGEYGGWYKACKVDSPTVTTTLKNLG 477

  Fly   445 ALYRRQGMFEAAETLEDCAMRSKKEAYDLAKQTKLSQLLTSNEKRRSKAIKEDL 498
            |||||||.||||||||:.|:||:|:..|.|.:.:::::|...|.|..:..:|.|
Zfish   478 ALYRRQGKFEAAETLEEAALRSRKQGLDTAHKQRVAEVLGDPEVREKQRSRESL 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klc	NP_524049.1	TPR	183..>391	CDD:440225	188/207 (91%)
		TPR repeat	187..214	CDD:276809	26/26 (100%)
		TPR repeat	228..256	CDD:276809	27/27 (100%)
		TPR repeat	270..298	CDD:276809	26/27 (96%)
		TPR repeat	311..341	CDD:276809	27/29 (93%)
		TPR repeat	354..381	CDD:276809	19/26 (73%)
klc1a	NP_001429199.1	None