Protein Alignment Klc and appbp2

DIOPT Version :10

• Sequence 1: NP_524049.1
• Gene: Klc / 39445
• FlyBaseID: FBgn0010235
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_997798.1
• Gene: appbp2 / 322995
• ZFINID: ZDB-GENE-030131-1715
• Length: 586
• Species: Danio rerio
• Alignment Length: 336
• Identity: 76/336 - (22%)
• Similarity: 138/336 - (41%)
• Gaps: 82/336 - (24%)

  Fly   103 QQKFQASEQLVAQLEEEKKHLEFMA------SVKKYDEN--------QEQDDACDKSRTDPVVEL 153
            :::|:.:|||:       ||..|:|      ...||.:.        ...|:.|..      |.:
Zfish   259 KREFRKAEQLI-------KHAVFLAREHFGHKHPKYSDTLLDYGFYLLNVDNICQS------VTI 310

  Fly   154 FPDEENEDRHNMSPTPPSQFANQTS---------GYEIPARLRTLH------NLVIQYASQGRYE 203
            :                     ||:         |..|  .:.|.|      :.|.||:| |:::
Zfish   311 Y---------------------QTALDIRQSVFGGKNI--HVATAHEDLAYSSYVHQYSS-GKFD 351

  Fly   204 VAVPLCKQALEDLERTSGHDHPDVATMLNILALVYRD-----QNK------YKEAANLLNDALSI 257
            .|:...::|::.:......:|..:|:...:.||:..:     .||      .:||.:|...:|.:
Zfish   352 TALFHAERAIDIITHILPEEHLLLASSKRVKALILEEIAIDCHNKETEERLLQEAHDLHLSSLQL 416

  Fly   258 RGKTLGENHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLC 322
            ..|..||.:...|....||..||....|:|:||.:..:|::|:|::||::..:||..:.:||.|.
Zfish   417 AKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLY 481

  Fly   323 Q-NQGKYDEVEKYYQRALDIYESKLGPDDPNVAKTKNNLAGCYLKQGRYTEAEILYKQVLT---R 383
            . :..:||:.|:.|.|::.|.:...|.....:......|...|...|.| |....|..:|:   |
Zfish   482 NYDMNQYDDAERLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSVGNY-EKVFEYHNILSNWNR 545

  Fly   384 AHEREFGAIDS 394
            ..:|:|...|:
Zfish   546 LRDRQFAVADA 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klc	NP_524049.1	TPR	183..>391	CDD:440225	58/228 (25%)
		TPR repeat	187..214	CDD:276809	9/32 (28%)
		TPR repeat	228..256	CDD:276809	8/38 (21%)
		TPR repeat	270..298	CDD:276809	10/27 (37%)
		TPR repeat	311..341	CDD:276809	10/30 (33%)
		TPR repeat	354..381	CDD:276809	6/26 (23%)
appbp2	NP_997798.1	TPR_12	290..363	CDD:315987	16/102 (16%)
		TPR_12	427..504	CDD:315987	25/76 (33%)
		TPR repeat	429..457	CDD:276809	10/27 (37%)
		TPR repeat	470..501	CDD:276809	10/30 (33%)