Protein Alignment Klc and Klc3

DIOPT Version :10

• Sequence 1: NP_524049.1
• Gene: Klc / 39445
• FlyBaseID: FBgn0010235
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_006228441.1
• Gene: Klc3 / 171549
• RGDID: 621432
• Length: 516
• Species: Rattus norvegicus
• Alignment Length: 391
• Identity: 245/391 - (62%)
• Similarity: 300/391 - (76%)
• Gaps: 13/391 - (3%)

  Fly     3 QMSQDEIITNTKTVLQGLEALRVEHVSIMNGIAE----------VQKDNEKSDMLRKNIENIELG 57
            :::.:|::..|:.|:|||||||.||.|:...:||          |:...||..::..::|.||||
  Rat    17 RLNPEELVRQTRQVVQGLEALRAEHHSLAGHLAEALAGPGPVAGVELLEEKQQVVNHSLEAIELG 81

  Fly    58 LSEAQVMMALTSHLQNIEAEKHKLKTQVRRLHQENAWLRDELANTQQKFQASEQLVAQLEEEKKH 122
            |.||||::||::|:..:||||.:|:.|.|||.|||.|||:||..||::.:|||:.||||||||.|
  Rat    82 LGEAQVLLALSAHVGVLEAEKQRLRAQARRLAQENTWLREELEETQRRLRASEEAVAQLEEEKSH 146

  Fly   123 LEFMASVKKYDENQEQDDACDKSRTDPVVELFPDEENEDRHNMSPTPPSQFANQTSGYEIPARLR 187
            |:|:..:::||..:|........|.|.:..|||.||.|.:   .|......|.|..|||||||||
  Rat   147 LQFLGQLRQYDPPEESQRPDSPPRRDSLASLFPSEEEEKK---GPEAAGAAAAQQGGYEIPARLR 208

  Fly   188 TLHNLVIQYASQGRYEVAVPLCKQALEDLERTSGHDHPDVATMLNILALVYRDQNKYKEAANLLN 252
            ||||||||||||||||||||||:||||||||:|||.||||||||||||||||||||||||..||:
  Rat   209 TLHNLVIQYASQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLH 273

  Fly   253 DALSIRGKTLGENHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALEIREKVLGKDHPDVAKQLNN 317
            |||.||.:|||..|||||||||||||||||||:|::|||||:|||||||||||.|||||||||||
  Rat   274 DALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNN 338

  Fly   318 LALLCQNQGKYDEVEKYYQRALDIYESKLGPDDPNVAKTKNNLAGCYLKQGRYTEAEILYKQVLT 382
            ||||||||||:.:||::|.|||.|||:..||.||||||||||||..||||.:|.:||.|||::|:
  Rat   339 LALLCQNQGKFQDVERHYARALSIYEALGGPQDPNVAKTKNNLASAYLKQNKYQQAEELYKEILS 403

  Fly   383 R 383
            :
  Rat   404 Q 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klc	NP_524049.1	TPR	183..>391	CDD:440225	163/201 (81%)
		TPR repeat	187..214	CDD:276809	25/26 (96%)
		TPR repeat	228..256	CDD:276809	24/27 (89%)
		TPR repeat	270..298	CDD:276809	23/27 (85%)
		TPR repeat	311..341	CDD:276809	23/29 (79%)
		TPR repeat	354..381	CDD:276809	18/26 (69%)
Klc3	XP_006228441.1	Smc	<21..>148	CDD:440809	62/126 (49%)
		TPR	204..432	CDD:440225	163/201 (81%)
		TPR repeat	208..235	CDD:276809	25/26 (96%)
		TPR repeat	249..277	CDD:276809	24/27 (89%)
		TPR repeat	291..319	CDD:276809	23/27 (85%)
		TPR repeat	332..362	CDD:276809	23/29 (79%)
		TPR repeat	375..403	CDD:276809	18/27 (67%)