Protein Alignment Pmm2 and pmm2

DIOPT Version :8

• Sequence 1: NP_648589.1
• Gene: Pmm2 / 39436
• FlyBaseID: FBgn0036300
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_956378.1
• Gene: pmm2 / 368229
• ZFINID: ZDB-GENE-030722-6
• Length: 250
• Species: Danio rerio
• Alignment Length: 240
• Identity: 136/241 (56%)
• Similarity: 171/241 (71%)
• Gaps: 3/241 (1%)

  Fly    12 LLLFDVDGTLTMPRSVVTPEFEEFFYSRVKPRATIGIVGGSDLEKMFEQLNGRKILNEFDFIFPE 76
            |.|||||||||..|...|.:..||. |::|.|..:|:||||||:|:.||| |..:::..|::|.|
Zfish    11 LCLFDVDGTLTAARQKATADMHEFL-SKLKQRVKVGVVGGSDLDKIKEQL-GDDVIDRVDYVFAE 73

  Fly    77 NGLVQIEGGKEVGKQNIIMHLGEETVKRFINFVLRYLSELDVPIKRGTFIEFRNGMMNVCPIGRQ 141
            ||||....||....|||..:|||:.::.||||.|.|||::.:|.||||||||||||:||.||||.
Zfish    74 NGLVAYRFGKLHSVQNIQAYLGEDILQEFINFCLNYLSKIKLPKKRGTFIEFRNGMLNVSPIGRS 138

  Fly   142 CTREERNMFAEYDIEHKVREKMIKDLKQEFADVDLTYSIGGQISFDVFPHGWDKTYCLRHIEAHY 206
            |:::||..|.|.|.:.|:||..:..||:|||...|.:||||||||||||.||||.|||..:|..
Zfish   139 CSQQERIEFFELDKKEKIRETFVSVLKEEFAGKGLAFSIGGQISFDVFPEGWDKRYCLGIVEKD- 202

  Fly   207 KFKEIHFFGDKTEPGGNDYEIYSDPRTISHRVYTPKDTQRILTEI 251
            .::.||||||||.||||||||:.|||||.|.|.:|:|||||..|:
Zfish   203 SYQHIHFFGDKTMPGGNDYEIFVDPRTIGHEVKSPEDTQRICREL 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pmm2	NP_648589.1	HAD-SF-IIB	12..234	CDD:273651	126/222 (57%)
		PMM	33..254	CDD:281343	124/220 (56%)
pmm2	NP_956378.1	PTZ00174	10..249	CDD:240305	136/241 (56%)
		HAD-SF-IIB	13..232	CDD:273651	126/222 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C249486310
eggNOG	1	0.900				E1_COG0561
Hieranoid	1	1.000
Homologene	1	1.000				H257
Inparanoid	1	1.050	269	1.000	Inparanoid score	I2929
OMA	1	1.010
OrthoDB	1	1.010				D1038583at2759
OrthoFinder	1	1.000				FOG0002039
OrthoInspector	1	1.000				T1054145
orthoMCL	1	0.900				OOG5_127648
Panther	1	1.100			LDO	PTHR10466
Phylome	1	0.910		0.800	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R935
TreeFam	1	0.960
ZFIN	0	0.000	Not matched by this tool.
	14	13.800