DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pmm2 and LOC100007686

DIOPT Version :9

Sequence 1:	NP_648589.1	Gene:	Pmm2 / 39436	FlyBaseID:	FBgn0036300	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_003198076.3	Gene:	LOC100007686 / 100007686	-ID:	-	Length:	271	Species:	Danio rerio

Alignment Length:	242	Identity:	121/242 - (50%)
Similarity:	164/242 - (67%)	Gaps:	3/242 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ILLLFDVDGTLTMPRSVVTPEFEEFFYSRVKPRATIGIVGGSDLEKMFEQL-NGRKILNEFDFIF 74
            :|.|||||||||.||..:.||.::|..: :|.:..||:|||||..|:.||| :|.:::.:||::|
Zfish    23 VLCLFDVDGTLTAPREKIDPELDDFIQA-LKQKVKIGVVGGSDYCKIAEQLGDGDEVIQKFDYVF 86

  Fly    75 PENGLVQIEGGKEVGKQNIIMHLGEETVKRFINFVLRYLSELDVPIKRGTFIEFRNGMMNVCPIG 139
            .|||.||.:.||.:.||.|..|||||.::..|||.|.|:..:.:|.|||||||||:|::|:.|||
Zfish    87 AENGTVQYKDGKLIFKQAIQNHLGEELLQELINFCLSYMGLIKLPKKRGTFIEFRSGVINISPIG 151

  Fly   140 RQCTREERNMFAEYDIEHKVREKMIKDLKQEFADVDLTYSIGGQISFDVFPHGWDKTYCLRHIEA 204
            |.||.|||..|:|.|...|:|||.:..|::|||...|.::.||.||||:||.||||..||..:|.
Zfish   152 RSCTLEERIEFSEIDKREKIREKFVAALQKEFAGKGLRFTRGGLISFDIFPEGWDKRLCLDVLEQ 216

  Fly   205 HYKFKEIHFFGDKTEPGGNDYEIYSDPRTISHRVYTPKDTQRILTEI 251
            . ....|:|||::|..|||||||:.||||:...|..|.||.|:..|:
Zfish   217 E-GLDTIYFFGNETSLGGNDYEIFEDPRTVGFSVSCPADTARLCREM 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pmm2	NP_648589.1	HAD-SF-IIB	12..234	CDD:273651	114/222 (51%)
Pmm2	NP_648589.1	PMM	33..254	CDD:281343	107/220 (49%)
LOC100007686	XP_003198076.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53697
OrthoDB	1	1.010	-	-		D1038583at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101634
Panther	1	1.100	-	-	O	PTHR10466
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.930