Protein Alignment eIF2beta and Eif2s2

DIOPT Version :10

• Sequence 1: NP_524043.1
• Gene: eIF2beta / 39433
• FlyBaseID: FBgn0004926
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_955412.1
• Gene: Eif2s2 / 296302
• RGDID: 735192
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 338
• Identity: 197/338 - (58%)
• Similarity: 230/338 - (68%)
• Gaps: 48/338 - (14%)

  Fly     7 FDPTLLKKKKKKKTTFDLDAALGLEDDTKKE------------DPQDEASAEGGAAAEEDNL--- 56
            ||||:.|||||||..|.||.    |.|.:.|            :|.:|...|   |.|||:.
  Rat     8 FDPTMSKKKKKKKKPFMLDE----EGDAQTEETQPSETKEVEPEPAEEKDVE---ADEEDSRKKD 65

  Fly    57 ------DLESFGKKKKKK--KKPFNMDEIEAAIPSFGGDDV---AASEEPEEEEINLDMDFSMAK 110
                  ||..|.:|||||  ||.|::||.|.||     .||   :.::||.|.|.:||:.....|
  Rat    66 ASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAI-----KDVKIESDAQEPAEPEDDLDIMLGNKK 125

  Fly   111 KKKKSKK-KELDELF-ADQADDDKSEDKENDE------DNSSTWFGSDRDYTYDELLKRVFEIIL 167
            ||||:.| .:.||:. .|:|.:|  ||.:.|:      .....|.||:|||||:|||.|||.|:.
  Rat   126 KKKKNVKFPDEDEILEKDEALED--EDSKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMR 188

  Fly   168 DKNPDMAAGRKPKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLPKHLLDFLLAELGTSGSMDGN 232
            :|||||.||.|.||||:||||:|||||||||.||.||.|.|||.|||||.|||||||||||:|||
  Rat   189 EKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGN 253

  Fly   233 QQLIIKGRFQPKQIENVLRRYIKEYVTCHTCRSPETILQKDTRLFFLQCESCGSRCSVASIKSGF 297
            .||:||||||.|||||||||||||||||||||||:|||||||||:|||||:|.|||||||||:||
  Rat   254 NQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGF 318

  Fly   298 QAVTGKRAAIRAK 310
            ||||||||.:|||
  Rat   319 QAVTGKRAQLRAK 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2beta	NP_524043.1	eIF2B_5	178..287	CDD:214764	91/108 (84%)
Eif2s2	NP_955412.1	eIF2B_5	199..308	CDD:214764	91/108 (84%)