Protein Alignment sti and DBF2

DIOPT Version :10

• Sequence 1: NP_001261768.1
• Gene: sti / 39429
• FlyBaseID: FBgn0002466
• Length: 1858
• Species: Drosophila melanogaster
• Sequence 2: NP_011606.3
• Gene: DBF2 / 852984
• SGDID: S000003324
• Length: 572
• Species: Saccharomyces cerevisiae
• Alignment Length: 471
• Identity: 133/471 - (28%)
• Similarity: 224/471 - (47%)
• Gaps: 105/471 - (22%)

  Fly    60 AICREGLLDAFCLLYNECDKDTLKKRDRNIAEFVNKFRPI---------------------IEET 103
            ::|:...|:.:|.:::..  .:.::|.:.:.|::.:...:                     :...
Yeast   105 SVCKMYFLEHYCDMFDYV--ISRRQRTKQVLEYLQQQSQLPNSDQIKLNEEWSSYLQREHQVLRK 167

  Fly   104 RKLRVNADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVV----TTSQVKEERDIMSIR 164
            |:|:....||.:.|.:|||.:|.|:|..::.|.::.|:|.:.|.::    .|..|..||||::..
Yeast   168 RRLKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTT 232

  Fly   165 NSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYV 229
            .||||:.|.|||||..:|||.||::||||..:|:..........||||::|:..|::.||::||.
Yeast   233 RSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYT 297

  Fly   230 HRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSL---------------------------- 266
            |||:||||.|||..|||||.|||.||....:..:.|:
Yeast   298 HRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYN 362

  Fly   267 -----------SPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICETTPF 320
                       |.||:|||:|.|:|:        ...:|    .:.||||:|.:.:|.:...|||
Yeast   363 QLREKEINYANSMVGSPDYMALEVLE--------GKKYD----FTVDYWSLGCMLFESLVGYTPF 415

  Fly   321 HEDNVHETYSKILSHCEESHLKELISFP--ADLKVSVNYR--NLIESLVTNPSKRL-SYERIKNH 380
            ...:.:|||..:      ...|:.:..|  :|.:.:.:.|  :||..|:.:|..|| |:|.:|..
Yeast   416 SGSSTNETYDNL------RRWKQTLRRPRQSDGRAAFSDRTWDLITRLIADPINRLRSFEHVKRM 474

  Fly   381 PFFSEIPWGSIRSQVPPIIPTVRSDDDTSNFEDGIRHKTRREQGVAK--------KSLTTNMKSN 437
            .:|::|.:.::||.:||..|.:.|:.|...|:|     ...|..:||        ..||..:..:
Yeast   475 SYFADINFSTLRSMIPPFTPQLDSETDAGYFDD-----FTSEADMAKYADVFKRQDKLTAMVDDS 534

  Fly   438 DFSGKDLPFIGYSFVH 453
            ..|.|   .:|::|.|
Yeast   535 AVSSK---LVGFTFRH 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	Protein Kinases, catalytic domain	111..452	CDD:473864	124/396 (31%)
		SMC_prok_B	481..1254	CDD:274008
		C1	1389..1440	CDD:410341
		CNH	1509..1779	CDD:459938
DBF2	NP_011606.3	MobB_Sid2p-like	85..172	CDD:439271	7/68 (10%)
		STKc_Sid2p_like	165..547	CDD:270751	127/407 (31%)