Protein Alignment sti and KIN82

DIOPT Version :10

• Sequence 1: NP_001261768.1
• Gene: sti / 39429
• FlyBaseID: FBgn0002466
• Length: 1858
• Species: Drosophila melanogaster
• Sequence 2: NP_010015.3
• Gene: KIN82 / 850453
• SGDID: S000000687
• Length: 720
• Species: Saccharomyces cerevisiae
• Alignment Length: 523
• Identity: 151/523 - (28%)
• Similarity: 251/523 - (47%)
• Gaps: 131/523 - (25%)

  Fly    28 AKPAGSASGSGIP-------ASTRRSIVPVSTT---SAAVAEAI--CREGLL--DAFCLLYNECD 78
            |.|..:.|.|..|       :.||:..:|::.|   ..|.:|..  .::||:  |...|......
Yeast   229 ASPLANLSLSNSPIDSPRKNSETRKDQIPMNITPRLRRAASEPFNTAKDGLMREDYIALKQPPSL 293

  Fly    79 KDTLK-KRDRNI--AEFVNKFRPIIEETR---KLRVNADDFLIKTLIGQGYFGNVHLVVERQTND 137
            .|.:: :|.|.:  ..|.|||:.|..|.:   |:|          |:|||..|.|:||.||.||.
Yeast   294 GDIVEPRRSRRLRTKSFGNKFQDITVEPQSFEKIR----------LLGQGDVGKVYLVRERDTNQ 348

  Fly   138 IYAMKKIKK-SVVTTSQVKE---ERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLL-SL 197
            |:|:|.:.| .::...::|.   |::|::..:..:::.|.::||..|.|||.|||..||:.. :|
Yeast   349 IFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRAL 413

  Fly   198 MSRHGP-FDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADF-------GNA 254
            .:|... ..|:.|:||.:|:..||..||.:|:::||:||||||:.:.||:.|:||       |:.
Yeast   414 QTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSK 478

  Fly   255 AALDRDGHVLSL----------SPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGII 309
            ....:|...|..          |.|||.:|:|||:::            ......:.|:|::||:
Yeast   479 KPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIR------------GNGHTAAVDWWTLGIL 531

  Fly   310 GYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVT-NPSKRLS 373
            .||::...|||..||.:||:|.||:       |: :.||.|.:||.|.::||:.|:. |.:|||.
Yeast   532 IYEMLFGCTPFKGDNSNETFSNILT-------KD-VKFPHDKEVSKNCKDLIKKLLNKNEAKRLG 588

  Fly   374 YER----IKNHPFFSEIPWGSIRSQVPPIIPTVRSDDDTSNFEDGIRHKTRREQGVAKKSLTTNM 434
            .:.    ||.||||.::.|..:|:|.||:||.:
Yeast   589 SKSGAADIKRHPFFKKVQWSFLRNQDPPLIPAL-------------------------------- 621

  Fly   435 KSNDFSGKDLPFIGYSFVHMEKSAISATTDEKLQEKLKELLQKLKTRE-----------NEISML 488
              || :|.:||||.....|.:::::|       :::.|...:|:...:           |.:|:.
Yeast   622 --ND-NGCELPFILSCNKHPKRNSVS-------EQETKMFCEKVANDDEIDEADPFHDFNSMSLT 676

  Fly   489 KQD 491
            |:|
Yeast   677 KKD 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	Protein Kinases, catalytic domain	111..452	CDD:473864	117/368 (32%)
		SMC_prok_B	481..1254	CDD:274008	4/22 (18%)
		C1	1389..1440	CDD:410341
		CNH	1509..1779	CDD:459938
KIN82	NP_010015.3	STKc_phototropin_like	322..623	CDD:270726	112/364 (31%)