Protein Alignment sti and PRKX

DIOPT Version :10

• Sequence 1: NP_001261768.1
• Gene: sti / 39429
• FlyBaseID: FBgn0002466
• Length: 1858
• Species: Drosophila melanogaster
• Sequence 2: NP_005035.1
• Gene: PRKX / 5613
• HGNCID: 9441
• Length: 358
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 116/314 - (36%)
• Similarity: 169/314 - (53%)
• Gaps: 40/314 - (12%)

  Fly   112 DFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIK-KSVVTTSQ---VKEERDIMSIRNSEWLINL 172
            ||.....:|.|.||.||||.|:.....:|:|.:. ..|:...|   |..|:.::...:..:||.|
Human    48 DFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRL 112

  Fly   173 QYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYVHRDIKPEN 237
            .:.:.|...||::|||:|||:|.|.:...|.|......||.||:..|:..||....|:||:||||
Human   113 FWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPEN 177

  Fly   238 ILIDRFGHIKLADFGNAAAL-DRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSC 301
            ||:||.|||||.|||.|..| ||     :.:..|||:|:|||::|       ||. |  .|.|
Human   178 ILLDRDGHIKLTDFGFAKKLVDR-----TWTLCGTPEYLAPEVIQ-------SKG-H--GRAV-- 225

  Fly   302 DYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIES-LV 365
            |:|::||:.:|::....||.:||....|.|||:        ..|.||..|...|  ::||:. ||
Human   226 DWWALGILIFEMLSGFPPFFDDNPFGIYQKILA--------GKIDFPRHLDFHV--KDLIKKLLV 280

  Fly   366 TNPSKRLSYER-----IKNHPFFSEIPWGSI--RSQVPPIIPTVRSDDDTSNFE 412
            .:.::||...:     :|:|.:|..:.|.::  |...|||:|.:..|.||||||
Human   281 VDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFE 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	Protein Kinases, catalytic domain	111..452	CDD:473864	116/314 (37%)
		SMC_prok_B	481..1254	CDD:274008
		C1	1389..1440	CDD:410341
		CNH	1509..1779	CDD:459938
PRKX	NP_005035.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34
		STKc_PRKX_like	47..338	CDD:270763	116/314 (37%)