Protein Alignment sti and Erc2

DIOPT Version :9

• Sequence 1: NP_001261768.1
• Gene: sti / 39429
• FlyBaseID: FBgn0002466
• Length: 1858
• Species: Drosophila melanogaster
• Sequence 2: XP_017455492.2
• Gene: Erc2 / 259269
• RGDID: 708372
• Length: 1136
• Species: Rattus norvegicus
• Alignment Length: 1207
• Identity: 257/1207 - (21%)
• Similarity: 457/1207 - (37%)
• Gaps: 356/1207 - (29%)

  Fly   453 HMEKSAISATTDE---KLQEKLKELLQKLKTRENEISMLKQDLLRAQQSLRKTDNKSQVVADAKM 514
            |...|.:....|.   .||.:||||     .|||       ||||.:..::          |:|
  Rat   133 HQVPSMLRQVRDSTMLDLQAQLKEL-----QREN-------DLLRKELDIK----------DSK- 174

  Fly   515 EIKKLQQIIKEKTMELTTCKTQIKTLQSSAKIDEEMWSKKEATITDLLRLNRQKYEEAKIASEQR 579
                           |.:....|||..|.....|.:..|:||....:|:      |:.:::.|:.
  Rat   175 ---------------LGSSMNSIKTFWSPELKKERVLRKEEAARMSVLK------EQMRVSHEEN 218

  Fly   580 YEKQLADKKQELASTLQKLDARELEFNAKFEECKHLSMKLQNYKDMLQQIKEQN--LKSETNHEE 642
                            |.||||         ..|||.:.:|..:|.|:..::.|  |:.|:.:..
  Rat   219 ----------------QLLDAR---------RTKHLQLTIQALQDELRTQRDLNHLLQQESGNRG 258

  Fly   643 QRRQMAELYEQKLTDLRKKVRDSQDTN---RRMTMEIKEIRTEL--------DESISS------- 689
            ......||.|:....|:.: .|.|...   .|.|:|..|:|.|.        ||||..
  Rat   259 AEHFTIELTEENFRRLQAE-HDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS 322

  Fly   690 ----SKSTQEAKNATER---------NIEEILRR-------LNEEIASNNELHAEKVK---LETK 731
                |||.::....|.|         ::|.||.:       |.||:...::|..|..|   |:|.
  Rat   323 KGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTV 387

  Fly   732 LQLKENETQEVRAECHRLERELQLAECRCQLAESSLATQVSPYETAPGSLTELNAIEDQLRADLL 796
            :::|:.:...:......||.|:|:.:....|.......::...|........:....|||:.: |
  Rat   388 IEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQE-L 451

  Fly   797 AAKESENHQKGRADQLQTLVTKLEQMLERFNEQSLSPTKSHSSRKQEGETVGDMLERQNEK---L 858
            :.||||         |..|.||||.:           :..:|..||..|.:.:.|..:.::   |
  Rat   452 SKKESE---------LLALQTKLETL-----------SNQNSDCKQHIEVLKESLTAKEQRAAIL 496

  Fly   859 EDKLAAVREQMIVERQAARTANLSLWKVEKQLEEALSEKKLLARRMELTEDRIKKVQNASDEAQR 923
            :.::.|:|.: :.|:::      .|.|..|||::...||..||..:...:|.::..:...:..|:
  Rat   497 QTEVDALRLR-LEEKES------FLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQK 554

  Fly   924 MLKTSQEETRQRESRIEELKQELAAAKRDVLKEHRQWEKAEQERMKCKSEIIEHLANVHRLEQQE 988
            .::..||:.|.::.::..||..:.:.:.|...........| |.:..|..|||.|.     ||:|
  Rat   555 KIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLE-EALSEKERIIERLK-----EQRE 613

  Fly   989 TELRQKLRQIQSRFDGVTLEQKNTIRELQEEREKSRKANDSCLVLQKELKQLTDNFQRLK-YACS 1052
            .:.|::|.:|:|            .|  :|.::...|.|    .||.||.:...:...|| :|.|
  Rat   614 RDDRERLEEIES------------FR--KENKDLKEKVN----ALQAELTEKESSLIDLKEHASS 660

  Fly  1053 ITDSQLTEVETMLKSEQERNKSQKSQLDTLHEKLRERNDQL-TDLRKQLTTVESEKRLAEQRAQV 1116
            :..:.|.. ::.|||.:...:.:|.:.:.|..:|:::.:|| ..:......:|.:.|:..:.|..
  Rat   661 LASAGLKR-DSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADR 724

  Fly  1117 LASEIDELRLNLKEQQKKLVAQQDQLVEQTNALFATQERAELLDGQNANYEAQT----ADSNREM 1177
            | .::|:.....:::..|..|:.|:|:|   .|...:......|.:.|..|:.|    .|.|:::
  Rat   725 L-KQLDKEASYYRDECGKAQAEVDRLLE---ILKEVENEKNDKDKKIAELESLTLRHMKDQNKKV 785

  Fly  1178 VSL-------KEENARILSELFHKKEEV----GNLQAE--IRGLESAQANL---HAEIDSLQDTL 1226
            .:|       |::||::|.|:..:::.:    .:||.|  :..||..:..|   .|.:.|.|.:|
  Rat   786 ANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSL 850

  Fly  1227 AEKEQFYVQRDIKSNATLAQHKKLIDYLQLKVE----------------DLSA-KKKKTLADKLF 1274
            ||||...      :|..:.:.|:|.:.|::|.|                :||| |||||
  Rat   851 AEKEAHL------ANLRMERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKT------ 903

  Fly  1275 GSSHTNKENVSPNDVESSILYRALKEELKREQKMNSLLKEQLAQLNGTATL-RSPRKSAAVNGDS 1338
                  :|.|.....|...|...||:::.|.:|     :...:.:..|... .||..:|..:|.|
  Rat   904 ------QEEVMALKREKDRLVHQLKQQVYRPRK-----QPPCSNIPCTCDAGYSPDFTAKYHGSS 957

  Fly  1339 -DAPKQRPVSIAALPRSPQKQQQPLKRTTSQVELKTTAEKPTKVTIENQAHHRFELALQESKVDA 1402
             ||...                   :|:.:|..:|..|:.      .:..||.:.
  Rat   958 YDAYMG-------------------QRSQTQNRMKLMADN------YDDDHHHYH---------- 987

  Fly  1403 VNCVVCEKAVVAGSPFWKCKECKDVTHRKCRSNVQSHCGSTKPTAPSADDLSSIQSVSSLTLDSV 1467
                                  ....|...||..:|...:.:   ||.|.||
  Rat   988 ----------------------HHHHHHHHRSPGRSQHSNHR---PSPDQLS------------- 1014

  Fly  1468 DVAGGTTSGGEYIGSLVYSSDGAEDQARKEIEVNCAFEVAEQQILLLGCNTGLYAYHLDSQRLVH 1532
                                    :...|.|..:|:      .:|::.|:..|:..:    :.:|
  Rat  1015 ------------------------EGLAKRIAQHCS------DVLIIYCSLALFFVY----QWLH 1045

  Fly  1533 ISGLE------SVSCMSICKRLAKAIMVGTVGEKLYQ 1563
            .:|.:      |:|| ||  |.::.:.:|..|:..|:
  Rat  1046 AAGRKGREFSLSLSC-SI--RFSETVPIGCTGKTEYE 1079

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357
		S_TKc	113..383	CDD:214567
		Smc	487..1222	CDD:224117	176/802 (22%)
		CNH	1503..1774	CDD:279162	14/67 (21%)
Erc2	XP_017455492.2	Cast	151..924	CDD:401982	211/917 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910