DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sti and orb6

DIOPT Version :9

Sequence 1:	NP_001261768.1	Gene:	sti / 39429	FlyBaseID:	FBgn0002466	Length:	1858	Species:	Drosophila melanogaster
Sequence 2:	NP_593165.1	Gene:	orb6 / 2543441	PomBaseID:	SPAC821.12	Length:	469	Species:	Schizosaccharomyces pombe

Alignment Length:	396	Identity:	140/396 - (35%)
Similarity:	212/396 - (53%)	Gaps:	70/396 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 RKLRVNADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVV----TTSQVKEERDIMSIR 164
            |:.|::.:||....:||:|.||.|.||.:..|..|||||.:.|:.:    ..:.||.|||::...
pombe    84 RRTRLSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLVES 148

  Fly   165 NSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYV 229
            :|.|:::|.|||||:..|||:||::|||||::::..:..|.||:.|||:||..:|:..:|.|||:
pombe   149 DSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADVHRMGYI 213

  Fly   230 HRDIKPENILIDRFGHIKLADFG----------------------------------------NA 254
            ||||||:||||||.|||||:|||                                        ..
pombe   214 HRDIKPDNILIDRDGHIKLSDFGLSTGFYKQDQSASYMKPRTGNTVKRGQMVDAIWLTMSSKDKM 278

  Fly   255 AALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICETTP 319
            |...::..|::.|.||||||||||:.       |.:....     .||:||:|.|.:|.:....|
pombe   279 ATWKKNRRVMAYSTVGTPDYIAPEIF-------LQQGYGQ-----DCDWWSLGAIMFECLIGWPP 331

  Fly   320 FHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRLSYE---RIKNHP 381
            |..:|.||||.||:      :.:|.::||.|:.:|:..|:|::.|:|:...||...   .|..||
pombe   332 FCSENSHETYRKII------NWRETLTFPNDIHLSIEARDLMDRLMTDSEHRLGRGGAIEIMQHP 390

  Fly   382 FFSEIPWGSIRSQVPPIIPTVRSDDDTSNFE-DGIRHKTRREQGVAKKSLTTNMKSNDFSGKDLP 445
            ||:.|.|..||....|.||.::|..||..|. |.:....  ||.|.::..:.:.::  ....:|.
pombe   391 FFTGIDWDHIRETAAPFIPNLKSITDTHYFPVDELEQVP--EQPVTQQPASVDPQT--LEQTNLA 451

  Fly   446 FIGYSF 451
            |:||::
pombe   452 FLGYTY 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	138/389 (35%)
		S_TKc	113..383	CDD:214567	116/316 (37%)
		Smc	487..1222	CDD:224117
		CNH	1503..1774	CDD:279162
orb6	NP_593165.1	STKc_NDR_like_fungal	91..461	CDD:270778	138/389 (35%)
orb6	NP_593165.1	S_TKc	93..392	CDD:214567	116/316 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910