Protein Alignment sti and dgk-4

DIOPT Version :9

• Sequence 1: NP_001261768.1
• Gene: sti / 39429
• FlyBaseID: FBgn0002466
• Length: 1858
• Species: Drosophila melanogaster
• Sequence 2: NP_501476.2
• Gene: dgk-4 / 177667
• WormBaseID: WBGene00006483
• Length: 1339
• Species: Caenorhabditis elegans
• Alignment Length: 1151
• Identity: 197/1151 - (17%)
• Similarity: 383/1151 - (33%)
• Gaps: 352/1151 - (30%)

  Fly     1 MPPKMEPISVRTARL------NNLILGKGAGVCAKPAGS------------------------AS 35
            :|..::.||...:.|      .||.:.....||.||.||                        |.
 Worm   105 IPQHLQFISPENSILPHQWMEGNLPMPSKCSVCEKPCGSVRKLIDYRCIWCGCCVHDTCIGNLAR 169

  Fly    36 GSGIPASTRRSIVPVSTTSAAV-AEAICREGLLDAF----------CLLYNECDKDTLKKRDRNI 89
            ...:..|....|.|::...... ..|:.||   :|:          .:|.|....|:..:|
 Worm   170 ACSLGHSALSVISPLAMKEVTPNGTAVLRE---EAYGGDSPGGSPLIVLINAKSGDSQGQR---- 227

  Fly    90 AEFVNKFRPIIEETRKLRVNA-------------DDFLIKTLIGQGYFGNVHLVVERQTNDIYAM 141
              .:.|||.|:...:...:.|             :.|.:....|.|..|.|....:|    :...
 Worm   228 --IIKKFRRILNPIQVFDIIATGPDFALTFFSHLESFRVLVCGGDGTVGWVLSAFDR----LNLH 286

  Fly   142 KKIKKSVVTTSQVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGG-----DLLSLMSRH 201
            .|.:.:::......:...::.     |    .:||.|:..|..|:..|...     |..|:::..
 Worm   287 SKCQLAILPLGTGNDLARVLG-----W----GHAFYDDTLLPQVVRTMERAHTKMLDRWSVLAIE 342

  Fly   202 GPFDEDLARFYLAELTV--------------ALHTLHEMGYVHRDIKPENILIDRFGHIKLADFG 252
            || ..|..|.| .||.:              .:|..:::....||      |:....|.......
 Worm   343 GP-QADAVRRY-EELVIEKVRTFLEAEQTWDIIHAANQLCTTIRD------LVHSVSHTYSDLEN 399

  Fly   253 NAAALDRDGHVLSLSPVGTPDYIAPELLQTISTY--KLSKSMHDVSRIVSCDYWSMGIIGYELIC 315
            |...||.:      |.:|..|    .:.:..:|.  ||.:.|..:....:|    :...|:|
 Worm   400 NKLKLDDE------SRLGGSD----TMTENCNTLLGKLDRLMKSLKEDANC----LEESGFE--- 447

  Fly   316 ETTPFHEDNVHETYSKIL---------SHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKR 371
               |..:|:. .|..::|         ::..:...:|:||. |:..:..:||:  .:......:|
 Worm   448 ---PGDDDDC-STGDEMLKKRDSVVNRANSLKKAFREVISM-AEKGIDQHYRD--PNTACTKRER 505

  Fly   372 LSYERIKNHPFFSEIPWGSIRSQ---VPPIIPTVRS--DDDTSNFEDG-------IRHKTRREQG 424
            ...:|.|..|....|...::.|.   .||..|....  .||...|...       |.|.......
 Worm   506 FRKKRSKTTPSVLTISHSNLSSSSACSPPCSPAGEDPPQDDQKEFRSASCKATFEISHSQSSSSA 570

  Fly   425 VAKKSLTTNMKSNDFSGKDLPFIGYSFVH-----MEKSAISATTDEKLQEKL---KELLQKLKTR 481
            |. .:|.....:..:...:.|.||  .||     ..:...:|..|::..|.:   ||:.||..::
 Worm   571 VL-TALFNAQSARTYDELEKPSIG--TVHPPTPGATREPSTAYDDDEENENVENRKEIDQKSNSK 632

  Fly   482 ENEISMLKQDLLRAQQSLRKTDNKSQVVADAKMEIKKLQQIIKEKTMELTTCKTQIK-------- 538
            ::.:| ..:|:.:.      :.::.::.:|..:. |.::::..:....:.:...::|
 Worm   633 KSSVS-TPEDITKG------SPDRPRIYSDTTLN-KNMEKMKSQSLHPICSSADKMKQSHSDSSL 689

  Fly   539 ---------------------TLQSSAKIDEEMWSK-KE-------------------------- 555
                                 ||..:...|...||: ||
 Worm   690 YADYEHLEGSSSGCGAGASGSTLSPARASDSATWSRIKERKRTVGSDLGLSSSSHLRSCRNMLSG 754

  Fly   556 ----ATITDLLRLNRQKYEEAKIASEQRYEKQLADKKQELASTLQKLDARELEFNAKFEECKHLS 616
                :.|.::|.||      |::.|      |::.::...|:...::...:.:  ..|.:.|.:.
 Worm   755 FAGGSLIAEILLLN------ARVLS------QMSSRRNSAANIANQIPTSDCQ--TPFTQYKEMC 805

  Fly   617 MKLQNY----KDMLQQIKEQNLKSETNHEEQRRQM---------AELYEQKLTDLRKKVRDSQDT 668
            : :.||    .|....::..|.:.|:.....|.::         .||..:...:|.::::...|
 Worm   806 V-MNNYFGIGLDAKIALEFHNKREESEKTRSRSKLFMWYGILGGKELMHRTYRNLEQRIKLECD- 868

  Fly   669 NRRMTMEIKEIRTELDESISS----SKSTQEAKNATERNIEEILRRLNEEIASNNELHAEKVKLE 729
              .:.:::..::..:..:|.|    :......|:..|..::....|:.|.:|....:|....::
 Worm   869 --GVPIDLPSLQGIVILNIPSYSGGANFWGRNKDGPEFTVQSFDDRILEVVALFGVIHVATSRV- 930

  Fly   730 TKLQLKENETQEVRAECHRLERELQLAECR----CQLAESSLATQV--SPYETAPGSLTELNAIE 788
                     ...||.:.||      :|:||    ..|.:..:..||  .|:...||    :..|.
 Worm   931 ---------PNAVRLQNHR------IAQCRHVRIVILGDEPIPVQVDGEPWLQPPG----IMQIV 976

  Fly   789 DQLRADLLAAKESENHQKGRADQLQTLVTKLEQMLERFNEQSLSPTKSHSSRKQEGETVGDM--- 850
            .:.||.:||          |.......:.|.|:..|:     .|.|.:.|:....|....|:
 Worm   977 HKNRAQMLA----------RNPVFDATLKKWEEQKEK-----ASTTTAPSTPTALGAPTSDIISF 1026

  Fly   851 LERQNEKLEDKLAAVREQMIVERQAARTANLSLWKVEKQLEEALSEKKLLARRMELTEDRIKKVQ 915
            |.|..|.|.          ::|.:.||..      |...|.::|
 Worm  1027 LTRAREFLR----------LIEGEIARLG------VSSVLLQSL--------------------- 1054

  Fly   916 NASDEAQRMLK--TSQEETRQRESRIEELKQELAAAKR--DVLKEH 957
               |:|..::|  .|.||..:....:||.::.:|:.:|  ::|::|
 Worm  1055 ---DDANAIVKGGASGEEDPEAIDDLEEREETVASVERVVELLEDH 1097

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	70/382 (18%)
		S_TKc	113..383	CDD:214567	55/299 (18%)
		Smc	487..1222	CDD:224117	88/561 (16%)
		CNH	1503..1774	CDD:279162
dgk-4	NP_501476.2	C1	48..97	CDD:237996
		C1	121..171	CDD:197519	9/49 (18%)
		DAGKc	213..335	CDD:214487	23/140 (16%)
		DAGKa	806..965	CDD:214486	28/178 (16%)
		SAM_DGK-delta-eta	1186..1250	CDD:188906
		SAM	1188..1253	CDD:197735

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910