Protein Alignment sti and Erc1

DIOPT Version :9

• Sequence 1: NP_001261768.1
• Gene: sti / 39429
• FlyBaseID: FBgn0002466
• Length: 1858
• Species: Drosophila melanogaster
• Sequence 2: NP_444434.2
• Gene: Erc1 / 111173
• MGIID: 2151013
• Length: 1120
• Species: Mus musculus
• Alignment Length: 1125
• Identity: 234/1125 - (20%)
• Similarity: 440/1125 - (39%)
• Gaps: 287/1125 - (25%)

  Fly   440 SGKDLPFIGYSFVHMEKSAISATTDEKLQEKLKELLQKLKTRENEISMLKQDLLRAQQSLRKTDN 504
            ||.....|.:...|:...::::|....|::.....:..|:|:..|:       ||....|||.
Mouse   116 SGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEV-------LRENDLLRKD-- 171

  Fly   505 KSQVVADAKMEIKKLQQIIKEKTMELTTCKTQIKTLQSSAKIDEEMWS---KKEATITDLLRLNR 566
                              ::.|..:|::....|||          .||   |||..:
Mouse   172 ------------------VEVKESKLSSSMNSIKT----------FWSPELKKERAL-------- 200

  Fly   567 QKYEEAKIASEQRYEKQLADKKQELASTLQKLDARELEFNAKFEECKHLSMKLQNYKDMLQ---- 627
            :|.|.:||                   |:.|...|.::     ||.:|:.|.:|..:|.|:
Mouse   201 RKDEASKI-------------------TIWKEQYRVVQ-----EENQHMQMTIQALQDELRIQRD 241

  Fly   628 --QIKEQNLKSETN---------------HEEQRRQMAELY--EQKLTDLRKKVRDSQDTNRRMT 673
              |:.:|:..|.|.               |.|..||..||:  .:.|.::..::...:.|.....
Mouse   242 LNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARD 306

  Fly   674 MEIKEIRTELDESISSSKSTQEAKNATER---------NIEEILRRLNEEIASNN----ELH--- 722
            ..||::...|.....|:|:|:|....|.|         ::|.:|.:..:|   ||    |:|
Mouse   307 ESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKE---NNMLREEMHRRF 368

  Fly   723 ------AEKVKLETKLQLKENETQEVRAECHRLERELQLAECRCQLAESSLATQVSPYETAPGSL 781
                  |:...|:|.:::|:::...:......||.|:|:.:....|:......::...|......
Mouse   369 ENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHS 433

  Fly   782 TELNAIEDQLRADLLAAKESENHQ-KGRADQLQTLVTKLEQMLERFNEQSL-------SPTKSHS 838
            ..:....:||:.: |::|:::..: |.||..||:.:.:::|.|.|.:.:.|       :.|...|
Mouse   434 KFMKNKVEQLKEE-LSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFS 497

  Fly   839 SRKQEGETVGDMLERQNEKLEDKLAAVREQMIVERQAARTANLSLWKVEKQLEEALSEKKLLARR 903
            ..||..|.:.:.|..:    |.:.|.::.::...|.........|.|..||:::...||...|..
Mouse   498 DSKQHIEVLKESLTAK----EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGE 558

  Fly   904 MELTEDRIKKVQNASDEAQRMLKTSQEETRQRESRIEELKQELAAAKRDVLKEHRQWEKAEQERM 968
            :...:|.:...:...:..|:.::..||:.|.:|.::..||:.:.:.:.|...........| |.:
Mouse   559 IHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLE-EAL 622

  Fly   969 KCKSEIIEHLANVHRLEQQETELRQK-------------LRQIQSRFDGVTLEQKNTIRELQEE- 1019
            ..|...||.|.     ||::.:.|:|             ||:..|...|...|::.::.:::|.
Mouse   623 ADKERTIERLK-----EQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHA 682

  Fly  1020 --------REKSR---------KANDSCLVLQKELKQLTDNFQRLKYACSITDSQLTEVETMLKS 1067
                    ::.||         :..:.||.::.:||:..:.....:.:..::| ::.::|..:..
Mouse   683 SSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMSD-RIQQLEREISR 746

  Fly  1068 EQERNKSQKSQLDTLHEKLRERNDQLTDLRKQLTTVES--EKRLAEQRAQVLASEIDELRLNLKE 1130
            .::.:...::::|.|.|.|:|..::..|..|::..:||  .:::.:|..:|       ..|..||
Mouse   747 YKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKV-------ANLKHKE 804

  Fly  1131 Q-QKKLVAQ--------QDQLVEQT----NALFATQERAELLDGQNANYEAQTADSNREMVSLKE 1182
            | :||..||        :|.|.:.:    ::|....:|.|.|  :.|..|:....:.||||..:|
Mouse   805 QVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEEL--EEALRESVQITAEREMVLAQE 867

  Fly  1183 ENARILSELFHKKEEVGNLQAEIRGLESAQANLHAEIDSLQDTLAEKEQFYVQRDIKSNATLAQH 1247
            |:||..:|     ::|..|...:..::....::.|::.|.|.:|||||...      :|....:.
Mouse   868 ESARTNAE-----KQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHL------TNLRAERR 921

  Fly  1248 KKLIDYLQLKVE----------------DLSAKKKKT---------------------------- 1268
            |.|.:.|::|.|                :||:.||||
Mouse   922 KHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKL 986

  Fly  1269 LADKL----FGSSHTNKEN--VSPNDVESSILYRALKEELKREQKMNSLLKEQLAQLNGTATLRS 1327
            :||..    |.||.:|:.|  .||:.:...:|      ||.:.:   |.||..:..|......|.
Mouse   987 MADNYEDDHFRSSRSNQTNHKPSPDQIIQPLL------ELDQNR---SKLKLYIGHLTALCHDRD 1042

  Fly  1328 P------RKSAAVNGDSDAPKQRPVSIAALPRSPQKQ-QQPLKRTTSQVELKTTAEKPTKVTIEN 1385
            |      ...|:.|.|.:.        ||.....||. |:.|:....:||......:....||..
Mouse  1043 PLILRGLTPPASYNADGEQ--------AAWENELQKMTQEQLQNELEKVEGDNAELQEFANTILQ 1099

  Fly  1386 Q-AHHRFEL------ALQES 1398
            | |.|..::      ||:||
Mouse  1100 QIADHCPDILEQVVNALEES 1119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	3/11 (27%)
		S_TKc	113..383	CDD:214567
		Smc	487..1222	CDD:224117	168/836 (20%)
		CNH	1503..1774	CDD:279162
Erc1	NP_444434.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..54
		Cast	155..986	CDD:370855	189/934 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	801..840		10/38 (26%)
		RBD-FIP	1072..1112	CDD:370506	9/39 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910