Protein Alignment sti and rock1

DIOPT Version :9

• Sequence 1: NP_001261768.1
• Gene: sti / 39429
• FlyBaseID: FBgn0002466
• Length: 1858
• Species: Drosophila melanogaster
• Sequence 2: XP_002934180.3
• Gene: rock1 / 100496057
• XenbaseID: XB-GENE-984661
• Length: 1360
• Species: Xenopus tropicalis
• Alignment Length: 1666
• Identity: 406/1666 - (24%)
• Similarity: 685/1666 - (41%)
• Gaps: 483/1666 - (28%)

  Fly    66 LLDAFCLLYNECDKDTLKKRDRNIAEFVNKFRPIIEETRKLRVNADDFLIKTLIGQGYFGNVHLV 130
            |||....:..:.|...::| ::||..|:|:::..:.:.|.||:.|||:.:..:||:|.||.|.||
 Frog    30 LLDGLDAMVYDLDFPAMRK-NKNIDNFLNRYKDTMSKVRDLRMKADDYEVVKVIGRGAFGEVQLV 93

  Fly   131 VERQTNDIYAMKKIKK-SVVTTSQVK---EERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPG 191
            ..:.:..:||||.:.| .::..|...   ||||||:..||.|::.|.|||||:..||:|||||||
 Frog    94 RHKSSRKVYAMKLLSKLEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPG 158

  Fly   192 GDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAA 256
            |||::|||.: ...|..||||.||:.:||..:|.||::|||:||:|:|:|:.||:||||||....
 Frog   159 GDLVNLMSNY-DVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMK 222

  Fly   257 LDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICETTPFH 321
            ::|:|.|...:.|||||||:||:|::        ...|......||:||:|:..||::...|||:
 Frog   223 MNREGMVRCDTAVGTPDYISPEVLKS--------QGGDGYYGRECDWWSVGVFLYEMLVGDTPFY 279

  Fly   322 EDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRL---SYERIKNHPFF 383
            .|::..|||||::|      |..::||.|..:|...:|||.:.:|:...||   ..|.||.||||
 Frog   280 ADSLVGTYSKIMNH------KNSLTFPEDSDISKEAKNLICAFLTDREVRLGRNGVEEIKRHPFF 338

  Fly   384 --SEIPWGSIRSQVPPIIPTVRSDDDTSNFEDGIRHKTRREQGVAKKSLTTNMKSNDFSGKDLPF 446
              .:..|.::|..|.|::|.:.||.|||||:|....|...|.....|:         |.|..|||
 Frog   339 KNDQWAWETLRDTVAPVVPDLTSDIDTSNFDDLEEDKGDEETFPIPKA---------FVGNQLPF 394

  Fly   447 IGYSF-----------VHMEKSAISATTDEKLQEKLKELLQKLKTR-ENEISMLKQDLLRAQQSL 499
            :|:::           .:...:..|:|.|:.|.|.|::.:.:|:.: .||:.:
 Frog   395 VGFTYYSNRQYLDDPSANPNDNRSSSTVDKNLVENLQKNIYQLEEQLHNEMQL------------ 447

  Fly   500 RKTDNKSQVVADAKMEIKKLQQIIKEKTMELTTCKTQIKTLQSSAKIDEEMWSKKEATITDLLRL 564
                 |.::....:|...||.:|:||                    :|||.
 Frog   448 -----KDEMEQKCRMSNIKLDKIMKE--------------------LDEEG-------------- 473

  Fly   565 NRQKYEEAKIASEQRYEKQLADKKQELASTLQKLDARELEFNAKFEECKHLSMKLQNYKDMLQQI 629
            |::|..|:.:|..::.:..|..:..|.....::          :.|:.:::..::...||.|:..
 Frog   474 NQRKNLESLVAQTEKEKIMLQHRINEYQRKAEQ----------ESEKRRNVENEVSTLKDQLEDF 528

  Fly   630 KEQNLKSETNHEEQRRQMAELYEQKLTDLRKKVRDSQDTNRRMTMEIKEIRTELDESISSSKS-T 693
            |:   .|:|:|         :..:|:..|:|::.::.|.          :|||.|.::...|| |
 Frog   529 KK---ISQTSH---------ITNEKIAQLQKQLEEANDL----------LRTESDTAVRLRKSQT 571

  Fly   694 QEAKNATERNIEEILRRLNEEI--------ASNNELHAEKVKLETKLQLKENETQ-------EVR 743
            :.:|..::      |..||.|:        :|.:::..:...|:..|..:..:..       :::
 Frog   572 EMSKTVSQ------LEALNRELQDRCRLLESSKSQVEKDYFHLQAALDSERRDRSQGSEMIGDLQ 630

  Fly   744 AECHRLERELQLAECRCQLAESSLATQVSPYETAPGSLTELNAIEDQLRADLL--AAKESENHQK 806
            |....|:.||:..:...::|||                      |.:...|||  :.||..|.:.
 Frog   631 ARMASLQEELKHVKNNLEMAES----------------------ERKRAQDLLNNSEKEKNNLEI 673

  Fly   807 GRADQLQTLVTKLEQMLER-FNEQSLSPTKSH-SSRKQEGETVGDMLERQNEKLEDKLAAVRE-Q 868
            ....||:|    |:||||: .||..:  ||:. |.|.|..|             |:|..|:.| :
 Frog   674 DLNYQLKT----LQQMLEQEINEHKV--TKARLSDRHQSFE-------------EEKSVAMCEME 719

  Fly   869 MIV--ERQAARTANLSLWKVEKQ---LEEALSEKKLLARRMELTEDRIKKVQNASDEAQRMLKTS 928
            |.|  ||.|...|.....::|||   ||..|.:.:                       |:|
 Frog   720 MKVKGERAAKEKAENRRVEIEKQCSMLEFDLKQSR-----------------------QKM---- 757

  Fly   929 QEETRQRESRIEELKQELAAAKRDVLKEHRQWEKAEQERMKCKSEIIEHLANVHRLEQQETELRQ 993
            :..|:|||...||:||...           |.|...::|:..::|:.:|...|..|:..|.:|:|
 Frog   758 EHFTQQRERLEEEVKQLTL-----------QLEHETKKRIVTQNELNQHAGLVDTLKGSEKQLKQ 811

  Fly   994 KLRQIQSRFDGVTLEQKNTIRELQEEREKSRKANDSCLVLQKELKQLTDNFQRLKYACSITDSQL 1058
            ::               ||:.|.:.             :|:.||.|||..::.       .:.|:
 Frog   812 EI---------------NTLLEAKR-------------LLEFELGQLTKQYRG-------NEGQM 841

  Fly  1059 TEVETMLKSEQERNKSQKSQLDTLHEKLRERNDQLTDLRKQL-------TTVESEKRLAEQRA-- 1114
            .|::..|::||..:...|:|:..|.|::.|:.....:|.|::       .|:.::..|||.:|
 Frog   842 RELQDQLEAEQYFSTLYKTQVRELKEEVEEKTKHSHELEKRVHELYNDKDTLTAQLDLAETKAES 906

  Fly  1115 -QVLASEIDELRLNLKEQQKKLVAQ--QD--------QLVEQTNALFATQERAELLDGQNANYEA 1168
             |:..:.::|....:.::.|||.|:  ||        :.:|:||:....              :.
 Frog   907 EQLARTLLEEQYFEVNQENKKLSARSWQDNTEKDHTIRKLEETNSTLTK--------------DV 957

  Fly  1169 QTADSNREMVSLKEENARILSELF-HKKEEVGNLQAEI-------RGLESAQANLHAEIDSLQD- 1224
            ||.....|.:|   |.||.|.:.: .|:||:.||:...       :.|::...|..|||.:.:|
 Frog   958 QTLTKANEELS---EKARKLEQEYKEKEEEIYNLRNSYEKAINTEKTLKTQAVNKLAEIMNRKDF 1019

  Fly  1225 ------------TLAEKEQFYVQRDI-----KSNATLAQHKKLID--YLQLKVE---------DL 1261
                        ...|||...:|.|:     |.|..:|:::|.:|  .:||..|         .|
 Frog  1020 KLDRKKANTQDLRKKEKENRKLQLDLNQEKEKYNQMVAKYQKELDETLMQLTEESNYKNELQMQL 1084

  Fly  1262 SAKK------KKTLADKLFGSSHTNKENVSPNDVESSILYRALKEELKREQKMNSL---LKEQLA 1317
            .:|:      :..|||.......|:..::.|:|.:..|....::..|....:.|..   .|:|..
 Frog  1085 DSKESDIEQLRARLADLQLRMDSTSVASLQPDDTDGIIGESRIEGWLSIPNRGNIKRYGWKKQYV 1149

  Fly  1318 QLNGTATLRSPRKSAAVNGDSDAPKQRP----------------------VSIAALPRSPQKQQQ 1360
            .:       |.:|....|.:.:..:..|                      .:...:||..|....
 Frog  1150 VV-------SSKKILFYNDEQNKEQSSPSMVLDIDKLFHVRAVTQGDVYRANTEEIPRIFQILYA 1207

  Fly  1361 PLKRTTSQVELKTTAEKPTKVTIENQAHHRFELALQESKVDAVNCVVCEKAVVAGSPFW------ 1419
            ........|||: ..::..|....|...|.|...|...   ..||..|.|      |.|
 Frog  1208 NEGECRKDVELE-PVQQTEKTNFLNHKGHEFIPTLYHF---PANCEACAK------PLWHVFKPP 1262

  Fly  1420 ---KCKECKDVTHRKCRSNVQSHCGSTKPTAPSADDLSSIQSVSSLTLDSVDVAGGTTSGGEYIG 1481
               :|:.|    |.||..                |.|...:.:.|....|.||
 Frog  1263 PALECRRC----HVKCHK----------------DHLDKKEELISPCKVSYDV------------ 1295

  Fly  1482 SLVYSSDGAEDQARKEIEVNCAFEVAEQQILLLGCNTGLYAYHLDSQRLVHISGLESVSCMSICK 1546
                                    .:.:.:|||.|.        ..::...:|.|        .|
 Frog  1296 ------------------------TSARDMLLLACT--------QEEQTKWVSHL--------VK 1320

  Fly  1547 RLAKAIMVGTVGEKLYQCDYRQLESRCQSSSSCHKPVLETS 1587
            ::.|     |....|.:.:.|.:.:|..::.|..||...:|
 Frog  1321 KIPK-----TPPPTLVRGNQRTMSTRSSTNQSFRKPAKTSS 1356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	145/360 (40%)
		S_TKc	113..383	CDD:214567	119/276 (43%)
		Smc	487..1222	CDD:224117	164/788 (21%)
		CNH	1503..1774	CDD:279162	16/85 (19%)
rock1	XP_002934180.3	STKc_ROCK1	2..406	CDD:270772	158/400 (40%)
		Smc	<424..1107	CDD:224117	189/902 (21%)
		HR1_ROCK1	491..556	CDD:212029	14/96 (15%)
		ROCK_SBD	838..918	CDD:409019	19/79 (24%)
		PH_ROCK	1125..1231	CDD:269948	15/113 (13%)
		C1_ROCK1	1228..1296	CDD:410424	21/132 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920