Protein Alignment Smyd4-2 and SET5

DIOPT Version :10

• Sequence 1: NP_648574.1
• Gene: Smyd4-2 / 39414
• FlyBaseID: FBgn0036282
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_012077.1
• Gene: SET5 / 856614
• SGDID: S000001250
• Length: 526
• Species: Saccharomyces cerevisiae
• Alignment Length: 504
• Identity: 101/504 - (20%)
• Similarity: 177/504 - (35%)
• Gaps: 164/504 - (32%)

  Fly   150 SILIRLGEGEAALNDL-KLAINFGLELKSSVDYYLKMAKAYAVMGEPARAEISLKIAEKMPGCDA 213
            ::.|::|    .|||. :.|::.|.|..|.   :.|:.        |...||          ||
Yeast     2 TLTIKIG----TLNDSDQSAVHNGTENGSD---FRKIT--------PTEEEI----------CD- 40

  Fly   214 THIALCRKELSSVKPKPKEATSEQV-PQLAHGESAELVGASKVVRL----------VET----KD 263
             .:.|..||    :|..::||.:.: .::.....:..:.||:..::          :||    ||
Yeast    41 -DVVLLWKE----EPGTEDATIQHLYDRITERNQSWKLSASRFRKILNEHHLYDTDLETVSLYKD 100

  Fly   264 K----------------------GRFVVANEGLRTGDVLLFEEPVAACLEP--SYF----GTHCH 300
            |                      ||.:.|......|.::|.|......:.|  ..|    |..|.
Yeast   101 KIHFPKALDSDAKVEVKFIDDEHGRGLFAKRDFSKGQIILKENKPIVYIPPLDKLFLISNGKACA 165

  Fly   301 HCFKRLHT---------PVSCLHCSGIAFCSAQCMGEACS----SYHRFECEYMDLM-IGSGMSI 351
            .|.|.|:.         .:.|..|..| :||.:|.....|    .||.:....:|:: .|:....
Yeast   166 RCGKALYDLTQHKIMVHYLDCEVCKAI-WCSEKCKKAHASLHELLYHSWRSNRIDILHAGNWKRF 229

  Fly   352 LCFIALRIFTQAPSLEQGLATANLLFEHLCSHEEDRQPDDYLRR----------------ALMSG 400
            :.:.....||.|.|:  ||...::|.:.....:|..|....:.:                :|::|
Yeast   230 VNYCEKYCFTAAFSV--GLIYGSMLLDTTGEVKEQWQKLASISQRERIKLRDASGIGSTFSLLNG 292

  Fly   401 FLLRILQKSLYFGRRKTE-----------------GVNPTA---VELQVATALLGLLQVLQYNAH 445
            ..:...::|....::..|                 |..|.|   ::.:....::|...:.|||.
Yeast   293 TTVHTEEESDNGTKKGVEKNIDDETVWEKCYELFCGAFPKASEEIDFEKFLTMIGTFNINQYNG- 356

  Fly   446 QIYQTQVTEEHRFDGSKTVYLAAGLYGTGSYFNHECWPSTACHFV--GKKLVLTATRPHRANELV 508
            |:|       |..                |:.||:|.|:.....|  .::|.|.|.:|.:..|.:
Yeast   357 QVY-------HWI----------------SFINHDCEPNAYIEQVEEHEELRLHARKPIKKGEQI 398

  Fly   509 AVNY-GPIFIKNNLKERQRSLRGRYSFSCSCMACQ------ENWPLLQK 550
            .:.| .|:   :.::.|:|.||..:.|.|.|..||      |..|.|:|
Yeast   399 RITYVNPL---HGVRLRRRELRVNWGFLCQCDRCQNELSTFERVPNLEK 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-2	NP_648574.1	BepA	87..205	CDD:443813	13/55 (24%)
		SET_SMYD4	249..541	CDD:380934	74/386 (19%)
		zf-MYND	299..338	CDD:460312	13/51 (25%)
SET5	NP_012077.1	SET	114..>147	CDD:394802	6/32 (19%)
		SET_SMYD	<352..429	CDD:380997	26/103 (25%)