Protein Alignment Lmx1a and lhx2a

DIOPT Version :10

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_017208320.1
• Gene: lhx2a / 795283
• ZFINID: ZDB-GENE-091118-109
• Length: 328
• Species: Danio rerio
• Alignment Length: 248
• Identity: 76/248 - (30%)
• Similarity: 110/248 - (44%)
• Gaps: 42/248 - (16%)

  Fly   274 LCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHH--TCYVRNSKLYCKMDY--DRLFGVKC 334
            :|.|||..|.|||.:...:..|||:||.|..|...|..  ||:.::..:|||.||  .|....:|
Zfish    12 VCAGCGALISDRFYLLAAERRWHERCLKCSACQTDLESELTCFSKHGDIYCKEDYYSRRFSSQRC 76

  Fly   335 SSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRH----------- 388
            :.|...|...|:||| ..:.|:||.||.|..|...|..|:.:.:::..::|..|
Zfish    77 ARCHLGISATEIVMR-ARDLVYHLSCFSCATCHKVLLTGDHYGMKETSVYCRAHIQRECHADLYY 140

  Fly   389 ---------------DLEKEMFLAA-------AAAQHCGFVGLDEEDL---LRPRDGRRGPKRPR 428
                           |.|..:..|.       :.|.|..: ..|..||   |..|...:..||.|
Zfish   141 SDMSSRETNSESHTYDEESPVHRARVRRRKNNSTADHIAY-SSDVSDLGVDLSERVSCQKSKRMR 204

  Fly   429 TILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKK 481
            |.....|.:..::.|..:..|..|..:.||:.|||:.||:||||||.|||.::
Zfish   205 TSFKHHQLRSMQSFFTHNHNPDAKDLKELAQKTGLTKRVLQVWFQNARAKFRR 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	23/55 (42%)
		LIM	333..388	CDD:413332	17/54 (31%)
		Homeodomain	425..481	CDD:459649	24/55 (44%)
lhx2a	XP_017208320.1	LIM	13..66	CDD:413332	21/52 (40%)
		LIM2_Lhx2_Lhx9	72..130	CDD:188763	17/58 (29%)
		Homeodomain	201..257	CDD:459649	24/55 (44%)