Protein Alignment Lmx1a and lhx4

DIOPT Version :10

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001116445.1
• Gene: lhx4 / 571943
• ZFINID: ZDB-GENE-060728-1
• Length: 391
• Species: Danio rerio
• Alignment Length: 364
• Identity: 121/364 - (33%)
• Similarity: 171/364 - (46%)
• Gaps: 76/364 - (20%)

  Fly   275 CEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSCCH 339
            |.||.|.|.|:|::.|.|.:||.:||.|..|...|...|:.|...:|||.|:.:.||.||:||..
Zfish    33 CAGCSQHILDKFILKVLDRHWHSKCLKCADCHALLADKCFSRAGNVYCKEDFFKRFGTKCASCQQ 97

  Fly   340 AILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQF-MLRDGQLFCYRHDLEKEMFLAAAAAQH 403
            .|.|.: |:|...:||:||.||.|..|...|..|::| ::.||:|.|      ||
Zfish    98 GIPPTQ-VVRKAQDFVYHLHCFACVMCSRQLATGDEFYLMEDGRLVC------KE---------- 145

  Fly   404 CGFVGLDEEDLLRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVV 468
                  |.|...:..|...|.|||||.:|::|.:..|:::..||||.|.|||.|:.:|||.:|||
Zfish   146 ------DYETAKQNDDSETGAKRPRTTITAKQLETLKSAYKNSPKPARHVREQLSSETGLDMRVV 204

  Fly   469 QVWFQNQRAKMKKIQRKA------------KQNGGSGGGSGSGRGTGNSSATDDKDTNDKE---- 517
            ||||||:|||.|::::.|            |:|.||.       .|...|:.||...:|.|
Zfish   205 QVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRNRGSS-------KTEKESSADDAGLSDSELSFR 262

  Fly   518 DKCVKQELGGDSSGYLGGLDSTFASQPLNPNLPFSPDDYPANSNDSFCSSDLSLDGSNFDQLDDD 582
            |..:..:| |.::|..|.:...                    ||.:..:...||||..  |...|
Zfish   263 DDQILSDL-GHANGLYGSVGDV--------------------SNGNMLNGSFSLDGGG--QPYHD 304

  Fly   583 ADSLSLNNLELQSTSSSGNQHSHSHSNPHDMLANLNNSL 621
            ..:.|...|. ||.||..:...|:     .:|.||..|:
Zfish   305 LRAGSPYGLP-QSPSSITSLPGHT-----PLLNNLGFSM 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	22/51 (43%)
		LIM	333..388	CDD:413332	23/55 (42%)
		Homeodomain	425..481	CDD:459649	32/55 (58%)
lhx4	NP_001116445.1	LIM1_Lhx4	33..84	CDD:188852	21/50 (42%)
		LIM2_Lhx3_Lhx4	92..147	CDD:188762	24/77 (31%)
		Homeodomain	161..217	CDD:459649	32/55 (58%)