Protein Alignment Lmx1a and Dfd

DIOPT Version :10

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Alignment Length: 659
• Identity: 137/659 - (20%)
• Similarity: 213/659 - (32%)
• Gaps: 208/659 - (31%)

  Fly    38 SMTASSGNSLHLSNS--NNNLPTSISGNNSPTATASLTGQ-HQQHQQQQHQQQQQHPHQQHQQHQ 99
            |||||:|   |:|.:  ......|:.|..:    ..:||. |..|..........|.|..| .|.
  Fly    44 SMTASTG---HMSGAVGGGAGVGSVGGGGA----GGMTGHPHSMHPADMVSDYMAHHHNPH-SHS 100

  Fly   100 QQHAASTTPVPINSCPTPTGHSPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAAS 164
            ..|.                || |....|||..:.::..:.||.|||               .|:
  Fly   101 HSHT----------------HS-LPHHHSNSAISGHHQASAGGYSSN---------------YAN 133

  Fly   165 AAAVAAPSPAGTSVATSQLGGAVAAAIAAAAAAAAAATTPTSTGPAATGSGNANGSGNGN----- 224
            |...:.|.....:.....||..|..|....:|.|..:......||||.....:||.|.|.
  Fly   134 ATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGAVL 198

  Fly   225 GNG--NGNGNGNGNGNGGGAATASAAAAS-------------KLSADCS----------GRTEVG 264
            |.|  .|:.||...|.|||..||:.:..|             .|...||          |..|:|
  Fly   199 GGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELG 263

  Fly   265 HIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRL 329
             :|.||..|.....||::.:                    .||:|.  |....|:.....:.|||
  Fly   264 -LKLEKRIEEAVPAGQQLQE--------------------LGMRLR--CDDMGSENDDMSEEDRL 305

  Fly   330 FGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEM 394
            .                                  ..|.|.:.|.             :|.:.::
  Fly   306 M----------------------------------LDRSPDELGS-------------NDNDDDL 323

  Fly   395 FLAAAAAQHCGFVGLDEEDLLRPRDGRR-----------------------GPKRPRTILTSQQR 436
                      |....||:.:....||.|                       .|||.||..|..|.
  Fly   324 ----------GDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQI 378

  Fly   437 KQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQR-------KAKQNGGSGG 494
            .:.:..|..:....|:.|..:|....||.|.:::||||:|.|.||..:       :.|....:|.
  Fly   379 LELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGN 443

  Fly   495 GSGSGRGTGNSSATDDKDTNDKEDKCVKQE----------LGGDSSGYLGGLDSTFASQPLNPNL 549
            .:...:.....:|:..:....::.:..:|:          :..||...:|.:.|:..:.|..|..
  Fly   444 PTPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAA 508

  Fly   550 PFSPDDYP------ANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSSGNQHSHSHS 608
            |.:...||      :|:|:         :||..:..:::.::.:|||....:.....|.|.|...
  Fly   509 PETTSSYPGSQQHLSNNNN---------NGSGNNNNNNNNNNSNLNNNNNNNQMGHTNLHGHLQQ 564

  Fly   609 NPHDMLANL 617
            ...|::.||
  Fly   565 QQSDLMTNL 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	7/51 (14%)
		LIM	333..388	CDD:413332	3/54 (6%)
		Homeodomain	425..481	CDD:459649	19/55 (35%)
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	19/55 (35%)