Protein Alignment Lmx1a and FHL1

DIOPT Version :10

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001427698.1
• Gene: FHL1 / 2273
• HGNCID: 3702
• Length: 339
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 46/198 - (23%)
• Similarity: 67/198 - (33%)
• Gaps: 44/198 - (22%)

  Fly   267 KC--EKNFELCEGCGQKIHDRFLMNVGDAN-------WHEQCLACCYCGMQL-HHTCYVRNSKLY 321
            ||  .::...|:||.:.|      ..||.|       ||:.|..|..|...: ..:.:.:....|
Human   107 KCTTREDSPKCKGCFKAI------VAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY 165

  Fly   322 CKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCY 386
            |...::..|...|..|..||....:..:..|   :|..||||..|...| .|::|...:.|.:|.
Human   166 CVTCHETKFAKHCVKCNKAITSGGITYQDQP---WHADCFVCVTCSKKL-AGQRFTAVEDQYYCV 226

  Fly   387 RHDLEKEMFLAAAAAQHCGFVGLDEEDLLRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCR 451
              |..|..     .|:.|.                 |.|.|.|...:..|.....|..:.|..|.
Human   227 --DCYKNF-----VAKKCA-----------------GCKNPITGKRTVSRVSHPVSKARKPPVCH 267

  Fly   452 KVR 454
            ..|
Human   268 GKR 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	14/59 (24%)
		LIM	333..388	CDD:413332	16/54 (30%)
		Homeodomain	425..481	CDD:459649	8/30 (27%)
FHL1	NP_001427698.1	None