Protein Alignment Lmx1a and lim-4

DIOPT Version :10

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_508669.1
• Gene: lim-4 / 180672
• WormBaseID: WBGene00002987
• Length: 355
• Species: Caenorhabditis elegans
• Alignment Length: 352
• Identity: 94/352 - (26%)
• Similarity: 135/352 - (38%)
• Gaps: 82/352 - (23%)

  Fly   240 GGAATASAAAASKLSADCSGRTEVGHIKCEKNFE------------------------------- 273
            |...::.:...|...:|||..|..|.:...:.|.
 Worm    28 GDYLSSPSLTTSDYVSDCSNLTVEGPVPANQEFSSSDESSVYISSALRLADYAFTPDDNIRIKPD 92

  Fly   274 ----LCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRL----- 329
                :|..|..:|.|:|.:::...|:||.||.|..|...|.:.|:.::...|||..|.|.
 Worm    93 AVIVICTQCQHQIQDKFFLSIDGRNYHENCLQCSTCENPLSNKCFYKDKTFYCKGCYFRTHVTST 157

  Fly   330 ------FGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRH 388
                  .|.||:||...|...:.|.| ..|:|:||.||.|..|:..|..||::.|::|.|.|.:|
 Worm   158 ASSCRELGPKCASCDRTIQATDWVRR-ARNYVYHLACFSCNQCKRQLSTGEEYALQEGNLLCKQH 221

  Fly   389 DLEKEMFLAAAAAQHCGFVGLDEEDLLRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKV 453
            .||.....:..::|                  :...||.||.....|....:..|::...|....
 Worm   222 FLELVEGDSGVSSQ------------------KAKTKRVRTTFAEDQLSVLQTYFNRDSNPDGAD 268

  Fly   454 REALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKD------ 512
            .|.:|..||||.||.||||||.||:.||..:|::  |.:|....|..|..:.|...|..
 Worm   269 LEKIASMTGLSKRVTQVWFQNSRARQKKWHQKSE--GDNGDSQRSSVGPSSPSQKSDSSSEMMYP 331

  Fly   513 ---TNDKEDKCVKQELGGDSSGYLGGL 536
               |...||..      .||...||.|
 Worm   332 TSVTTSVEDAI------PDSIVILGSL 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	17/51 (33%)
		LIM	333..388	CDD:413332	22/54 (41%)
		Homeodomain	425..481	CDD:459649	23/55 (42%)
lim-4	NP_508669.1	LIM	98..153	CDD:395333	19/54 (35%)
		LIM2_AWH	168..222	CDD:188765	21/54 (39%)
		Homeodomain	240..296	CDD:459649	23/55 (42%)