Protein Alignment CAH2 and Ca14

DIOPT Version :10

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_001103125.1
• Gene: Ca14 / 791259
• RGDID: 1599277
• Length: 337
• Species: Rattus norvegicus
• Alignment Length: 296
• Identity: 96/296 - (32%)
• Similarity: 151/296 - (51%)
• Gaps: 25/296 - (8%)

  Fly    16 ILICASLVLAQDFG----YEGRHGPEHWSEDYARCSGKHQSPINIDQVSAV-EKKFPKLEFFNF- 74
            :|:..:.:||.|.|    |||.||.:||...|..|.|..||||:|.....: :...|.::...:
  Rat     6 LLLKVTWILAADGGHHWTYEGPHGQDHWPASYPECGGNAQSPIDIQTDGVIFDPDLPTVQPHGYD 70

  Fly    75 KVVPDNLQMTNNGHTVLVKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTI-GSEDLI 138
            ::..:.|.:.||||||.:.:.      |::..|.|..|    |...|.|.|||:..|: |||..|
  Rat    71 QLGTEPLDLHNNGHTVQLSLP------PTLHLGGLPRK----YTAAQLHLHWGQKGTLKGSEHQI 125

  Fly   139 NNRAYPAELHVVLRNLE-YPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDRKGKS 202
            |:.|..||||||..:.| |...:.|..|..|:||:....:||:.....|:...:.|.::..|.:.
  Rat   126 NSEATAAELHVVHYDSESYGSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSHLHEVRYKDQK 190

  Fly   203 VNMTNPLPLGEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFR--LLTANDD 265
            .::. |..:.|.:.:.:|.:|.|.||||||||.:.|.|..|.....|:..||...:  |.:..:|
  Rat   191 TSVP-PFNVRELLPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEED 254

  Fly   266 ---HLKNNFRPIQPLNDRTLYKNYIEI-PIHNMGSI 297
               .|..|:|..||||.||::.::|:: |::..|.:
  Rat   255 PSEPLVQNYRVPQPLNQRTIFASFIQVGPLYTTGEM 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	34..286	CDD:459707	85/260 (33%)
Ca14	NP_001103125.1	alpha_CA_XII_XIV	29..278	CDD:239400	84/259 (32%)